An automatic solid phase extractor consisting of a vibration excitation device that provides vibration to a container filled with liquid, such as a pharmaceutical liquid; for use during drug discovery screening.
|Hitachi Koki (Tokyo)||Toi H||7/12/2006||1/31/2008|
A de novo iterative synthesis method for drug discovery that selects a compound having the desired pharmacophoric fit with a seed structure and synthesizing, assaying and comparing the compound to the structure to determine whether the compound has synthetically desirable properties.
|Cresset Biomolecular Discovery (Letchworth, UK), Cresset Therapeutics (Philadelphia, PA, USA)||Mackay M, Vinter J, Warrington B||6/19/2006||12/27/2007|
|EP 1859866, US 20070274871|
A well plate of non-unitary construction with side walls containing surface energy that provides a specific contact angle for aqueous solution contained in the well in an ambient environment to suppress meniscus formation; for growing cells and handling liquid samples in fields such as gene sequencing, combinatorial chemistry, drug discovery and proteomics, in automated and integrated systems.
|Genetix (New Milton, UK)||Jiang Y||5/23/2006||11/28/2007, 11/29/2007|
A robotic charge coupled device microscope for crystal recognition with a lighting system comprising a cluster of high brightness white LEDs; useful in structural, rational drug discovery, etc.
|University of California (Oakland, CA, USA)||Segelke BW, Toppani D||3/16/2005||11/6/2007|
An automatic storage apparatus for use in a drug discovery research environment, with a hand plate that moves in contact with the surrounding walls of the storage rack to obtain positional information of the storage rack in all directions.
|Tsubakimoto Chain Co. (Osaka, Japan)||Oshimo J, Shibata N||12/15/2005||6/28/2007|
|WO 2006036737, US 20060094059, EP 1797427|
A high-throughput, completely automated method of identifying a new therapeutic use for a test entity, e.g., a drug or drug candidate, involving testing the activity of the test entity against a protein complex in a cell and using the results obtained to identify new activity of the test entity; useful for large-scale drug discovery.
|Odyssey Thera (San Ramon, CA, USA)||MacDonald ML, Michnick SW, Owens S, Westwick JK, Yu H||9/22/2004||4/6/2006, 5/4/2006, 6/20/2007|
A dispensing apparatus comprising a chip remover arranged at the back of the dispensing mechanism to remove the used chip from the dispensing head and a chip holder to hold the unused chip; useful for drug discovery.
|Juki Corp. (Tokyo)||Okubo K||8/8/2005||2/22/2007|
|WO 2006133555, US 20060292549|
A system for testing the psychotropic activity of a compound comprising a silicon die having a surface for the growth of a neuronal network; useful for the automated screening of a compound in the field of drug discovery and neuroscience.
|Neurosilicon (Calgary, Canada)||Colicos MA||6/15/2005||12/21/2006, 12/28/2006|
A method of controlling the usage of reservoirs in a liquid handling area of an automated liquid handling system, involving determining and removing the content of a reservoir where the reagent is not expected to be used within a predetermined time interval; useful in drug discovery and development.
|Automation Partnership Cambridge (Royston, UK)||Grant PS, Oakeshott RBS||10/27/2004||5/3/2006|
A sample thawing apparatus that uses a sequence of several acicular nozzles to eject warm water to thaw a sample sealed in a container, such as deep-well plates or microtubes; for use in drug discovery research.
|Tsubakimoto Chain Co. (Osaka, Japan)||Oshimo J, Shibata N, Komada M||6/8/2004||12/22/2005|