A new DNA polymerase from Thermoanaerobacter tengcongensis having a specific amino acid sequence; useful for procedures requiring strand-displacing DNA synthesis and for reverse transcription.

New cubane nucleoside analog compounds that are viral DNA synthesis inhibitors; useful for treating viral infection, for example, hepatitis B, hepatitis C, HIV-1, herpes simplex viruses (HSV)-1, HSV-2, Epstein-Barr viral infection and cancer.

A new oligonucleotide primer comprising a 5' universal sequence, a 3' target-specific primer sequence or an extension sequence; useful for initiating polymerase-catalyzed DNA synthesis at a target region on a polynucleotide template.

A method for assaying Regenerating islet–derived family, member 4 (regenerating gene type 4) mRNA comprising using a primer and using the RNA transcript in turn as a template for DNA synthesis to amplify the RNA transcript in a chain-reaction.

A method of incorporating a fluorescent label during first-strand complementary DNA synthesis, comprising providing a primer with a fluorescent label attached to one end.

Inhibiting DNA synthesis, p44/p42 mitogen-activated protein kinase activation or tube formation in arterial endothelial cells, comprising contacting the arterial endothelial cells with ephrinB2.

In vitro flavonoid-rich tissue from Neomarica gracilis having antitumor activity, obtained from a tissue culture preparation, which alters flavonoid content of N. gracilis, where flavonoids-rich tissue comprises tectorigenin; useful as a cytostatic, antibacterial and/or fungicide.

A method for generating and expanding tissue-progenitor cells or mature tissue cells in culture,comprising culturing intact bone marrow or intact umbilical cord tissue in a cell differentiation medium.

An enhancer of tissue plasminogen activatorproduced by heat processing Bacillus natto culture solution; useful as a pharmaceutical or foodstuff for preventing thrombotic diseases.

A tissue-engineered skin manufacturing methodinvolving obtaining skin tissue, confecting anepidermal stem suspension with a specifiedconcentration, adding epidermal stem cells into atissue culture medium and carrying the cell viasubmerged culture.

Virus-free tissue culture and rapid propagation of sugarcane, comprising preparing a culture medium, selecting explant, sterilization, induction cultureof callus, differentiation culture, rooting cultureand transplantation.

A method for identifying and/or quantifying a target analyte present in sample by contacting the analyte with a probe molecule immobilized on a support and detecting the fluorescence signal induced in the spectral emission region of the fluorophore bound to the analyte.

A method of predicting the likelihood that a patient who is a candidate for treatment with an endothelial growth factor receptor (EGFR) inhibitor will respond to treatment, comprising determining the expression level of the transcript of STAT5B, or its expression product, in cancer cells obtained from the patient.

An interface apparatus for a differential mobility spectrometry (DMS) analyzer having electrodes with a gap to which ions are focused toward the median of the gap before and/or after at least one DMS analyzer.

A new set of descriptor genes combined into groups; useful for sub-categorizing breast cancers and identifying signals with bi- and multi-modal patterns across a set of high-throughput molecular data produced from biological samples.

A method of immobilizing a protein on a conductive resin film having a light transmittance of predetermined wavelength; useful for preparing biosensors.

A method of predicting the responsiveness of a tumor to treatment for anti-androgen therapy for prostate cancer by determining the androgen responsiveness microRNA expression profile of the tumor and correlating it to the therapeutic treatment.

A protein compound identification method involving building a protein interaction un-digraph, inputting a group of protein interaction data and setting a permitted maximum din of a shortest distance between a protein peak and a threshold value tin, which is between 0 to 1. The weight of each edge in a network is calculated, where the edge weight is defined as number of a public neighbor peak of two peaks of the edge. A seed is selected, when a candidate seed queue does not empty, and the seed is expanded as an initial state of an identified protein compound.

Biologically processing sewage by installing a micropore aeration plate on a barrier, fixing a dynamic film on the barrier and placing a sequencing batch biological film unit on the dynamic film.

A vector preparation comprising a double-stranded DNA molecule having 3'-termini, useful for preparing recombinant moleculeshaving only a single insert and for cloning PCR-amplified sequences.

A method of obtaining highly purified hydrophobic protein comprising extracting the retentate by microdiafiltration using a buffer-solution containing a detergent and subjecting the filtrate to hydroxyapatite column chromatography.

A new biologically active recombinant antibody or biologically active recombinant antibody fragment, used diagnostically/prognostically, therapeutically, for imaging, and/or for affinity purification of proteins.

A magnetic nanocrystal, where the surface of the nanocrystal is bonded with a biocompatible macromolecule and an alkyl-containing molecule simultaneously; useful, for example, in biological applications such as DNA/RNA, protein and cell separation and purification.

Producing an active mammalian N-acetylglucosaminyltransferase I (GnT1) protein in bacteria comprising expressing the mammalian GnT1 protein in bacteria and solubilizing, refolding and purifying the soluble mammalian GnT1 protein.

A method of protein concentration/purification comprising using the difference between the charge properties of protein and amino acid ions under the action of an electric field and through gel crossover to move the protein from one container to another.

A method of preparing a human single-chain variable gene fragment used for producing an antibody library by amplifying the human antibody heavy and light chain gene, digesting fragments and ligatingproducts, and amplifying the variable gene fragment.

A new substance comprising an antibody molecule fragment exhibiting affinity for the target molecule; useful for inducing an immune response against a pathogen and for treating a patient infected with aparticular pathogen.

A new single-chain fragment antibody-polypeptide fusion protein, where the single chain fragmentantibody is Her2-scFv; useful as an anti-cancersiRNA drug carrier.

A new biologically active recombinant antibody orbiologically active recombinant antibody fragment, used diagnostically/prognostically, therapeutically, for imaging, and/or for affinity purification of MNproteins/polypeptides.

New pegylated Abeta antibody fragment, useful for treating or preventing a condition selected from Alzheimer's disease, Down syndrome, stroke, brain hemorrhage or general mental debilitation.

A connective tissue growth factor (CTGF) gene expression inhibitor comprising pyrrole imidazole polyamide having N-methyl pyrrole, N-methyl imidazole and gamma-aminobutryic acid units; useful for treating CTGF-associated disease.

A method of regulating gene expression comprising introducing to gene depositories recombinant virus comprising an expression cassette including the regulatable transcription control element operably linked to an open reading frame of interest.

A method for recovering RNA from a formalin-fixed, paraffin-embedded biological tissue sample for studying gene expression in tumor tissues, involving de-paraffinizing the sample, contacting with a solution containing proteinase K, heating and adding proteinase K.

An antisense oligonucleotide structure inhibiting expression of SIRT1 and used for treating lung, hepatic and pancreatic cancers.

A new stress-responsive promoter polynucleotide useful in conferring in a plant a desired trait, preferably increased dehydration stress tolerance or increased mechanical stress tolerance.