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Vaccine Development
NOVAVAX Completes Enrollment Of Pivotal H1N1 Influenza Vaccine Clinical Trial In Mexico PDF Print E-mail
Tuesday, 09 March 2010 06:15

Novavax, Inc. (Nasdaq: NVAX) announced that the enrollment of over 3,500 subjects in Mexico has been completed in Stage B of its pivotal 2009 H1N1 virus-like-particle (VLP) pandemic influenza vaccine study. With the 1,000 subjects already enrolled in Stage A of the trial, the enrollment in this pivotal trial is now complete with over 4,500 subjects.

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Voluntary System Works For Swine Flu Vaccination PDF Print E-mail
Saturday, 13 February 2010 02:57

Social interaction between neighbours, work colleagues and other communities and social groups makes voluntary vaccination programs for epidemics such as Swine Flu, SARS or Bird Flu a surprisingly effective method of disease control.

New research published today, Thursday 11 February, in New Journal of Physics (co-owned by the Institute of Physics and German Physical Society), shows that contact with others can positively influence individuals to choose voluntary vaccination when considering the pros and cons.

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New York Times Examines WHO Process For Getting H1N1 Vaccines To Countries In Need PDF Print E-mail
Tuesday, 09 February 2010 05:35

The New York Times examines the WHO's role as a "clearinghouse" for getting the H1N1 (swine flu) vaccine to lower income nations. Though H1N1 has died down in North America and many wealthier nations "are trying to get rid of their [vaccine] surpluses," the virus continues to circulate in regions of North Africa, Central Asia and Eastern Europe, according to the newspaper.

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Novartis says swine flu vaccine boosts profit PDF Print E-mail
Saturday, 30 January 2010 00:09

Swiss pharmaceutical group Novartis posted on Tuesday an 8.0-percent jump in core annual net profit for 2009, saying that business had been boosted by sales of swine flu vaccine.

The Basel-based company also announced that Daniel Vasella would hand over the chief executive's post to Joe Jimenez, the head of the pharmaceuticals division, a job Vasella had combined with the chairmanship for 11 years.

Vasella, reporting core net profit for last year of 10.3 billion dollars (7.3 billion euros), said: "Novartis delivered an excellent performance in 2009 driven by strong underlying growth across our entire healthcare portfolio."

The Swiss giant's swine flu vaccine, launched alongside rival vaccine makers last year in response to the pandemic alert and state-led mass vaccination campaigns, helped overall net sales grow by seven percent to 44.3 billion, the company said.

"Vaccines and Diagnostics achieved exceptionally high sales by rapidly developing and delivering influenza A (H1N1) pandemic vaccines to address the public health threat," the company said.

Novartis said it expected to "maintain momentum" in 2010 with a strong array of newly launched drugs, and helped on by the 40-billion-dollar acquisition of dominant eye care group Alcon from Nestle this month.

"Over the past 12 months, we sustained our lead in approvals for new products, achieving more than 30 major new product approvals in the US, Europe and Japan," Vasella said.

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Start Of Phase II Study For Intranasal, Seasonal Influenza Vaccine DeltaFLU PDF Print E-mail
Thursday, 14 January 2010 06:15

AVIR Green Hills Biotechnology, the innovative biotech company based in Vienna, has started the New Year by embarking on the first clinical phase II study for the seasonal vaccine deltaFLU. The study will be carried out at the Medical University of Vienna. With this step, AVIR Green Hills has set yet another important milestone in the development of effective and modern influenza vaccines.

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Developing Countries Reassess Need For Donated H1N1 Vaccine PDF Print E-mail
Tuesday, 12 January 2010 05:41

As the number of H1N1 (swine flu) cases in some regions of the world continues to fall, developing countries scheduled to receive donated H1N1 (swine flu) vaccines from the WHO are reassessing just how many vaccines their countries need, the Canadian Press reports. "The WHO had hoped to provide vaccine for up to 10 percent of the populations of developing countries that wanted donated vaccine," the newspaper writes.

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Alternative Swine Flu Vaccination Provided By Insect Cells PDF Print E-mail
Thursday, 07 January 2010 06:21

Scientists in Vienna have developed a new technique for producing vaccines for H1N1, 'swine flu', based on insect cells. The research, published in the Biotechnology Journal, reveals how influenza vaccines can be produced faster than through the traditional method of egg-based production, revealing a new strategy for the fight against influenza pandemics.

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Recalled H1N1 Influenza Vaccine Lots Being Returned PDF Print E-mail
Thursday, 31 December 2009 06:12
The Alabama Department of Public Health is returning 5,200 doses of H1N1 influenza vaccine because of a voluntary recall from the manufacturer. The recall was issued for reasons unrelated to vaccine safety. These lots of vaccine were manufactured for infants and children 6 to 35 months of age, so this recall does not affect the nasal mist vaccine now being used in school clinics or injected doses administered to older children and adults.
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Flu Vaccine Shortages In Developing Countries Could Destabilize Global Security, Says Former WHO Deputy Head PDF Print E-mail
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Friday, 25 December 2009 20:08

"Flu vaccine shortages in developing nations may destabilize global security should the H1N1 [swine flu] virus become more deadly … David Heymann, a former deputy head of the World Health Organization" said Monday, Bloomberg reports. Heyman acknowledged the H5N1 (bird flu) virus helped to bolster the preparedness of developed nations for H1N1, but said there remain gaps in the ability to guarantee developing countries have access to vaccines.

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One Dose Of H1N1 Vaccine May Provide Sufficient Protection For Infants And Children PDF Print E-mail
Tuesday, 22 December 2009 05:52
One dose of vaccine may be effective to protect infants and children and reduce transmission of the H1N1 virus, according to a study in JAMA, published online today because of its public health implications. The study will appear in the January 6 print edition of the journal.
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NOVAVAX Presents Positive Clinical Results At The World Health Organization Conference, Geneva, Switzerland PDF Print E-mail
Tuesday, 23 February 2010 06:20

Novavax, Inc. (Nasdaq: NVAX) presented to the world's leading pandemic influenza vaccine experts a summary of the recent preliminary safety and immunogenicity data from its Pivotal 2009 A/H1N1 VLP pandemic influenza vaccine study in Mexico.

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Predicting Effectiveness Of Flu Vaccination Campaigns PDF Print E-mail
Wednesday, 10 February 2010 23:31

(doi:10.1016/j.vaccine.2010.01.002), published by Elsevier this month in Vaccine describes a new method that assesses the impact and cost-effectiveness of a range of vaccination options. The model was applied to the 2009 Influenza H1N1 outbreak and predicted accurately in real-time when the epidemic would peak and who should be prioritized for vaccination.

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Canada To Donate 5M Doses Of H1N1 Vaccine To WHO; Agency Has Received Commitment Of 200M Vaccines PDF Print E-mail
Tuesday, 02 February 2010 04:26

The Canadian government on Thursday announced the country would donate five million doses of H1N1 vaccines to the WHO from the country's current surplus, the Canadian Press reports (Branswell, 1/28). "[T]he donation will help the Geneva-based international body in its efforts to redistribute the vaccine to developing countries that couldn't afford their own supplies," the Globe and Mail reports (Alphonso, 1/28).

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Generation Of Fully Human Monoclonal Antibodies Neutralizing Influenza Virus Use Of SPYMEG As A Novel Human Lymphocyte Fusion Partner PDF Print E-mail
Thursday, 28 January 2010 07:25
Medical & Biological Laboratories Co., Ltd. (MBL), with the collaboration of Osaka University, has successfully generated several fully human monoclonal antibodies against pandemic A (H1N1 and H3N2) type influenza virus by utilizing blood samples from volunteers who were inoculated with influenza vaccine.

Professor Kazuyoshi Ikuta, Ph. D., at the Department of Virology, Research Institute for Microbial Diseases, Osaka University, has confirmed through in vitro experiments that the fully generated human antibodies can neutralize H3N2 influenza virus strains.
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Canada To Bridge Mexico's H1N1 Flu Vaccine Requirements PDF Print E-mail
Tuesday, 12 January 2010 05:43

The Honourable Leona Aglukkaq, Minister of Health, on behalf of the Government of Canada, has announced it will be providing five million doses of H1N1 flu vaccine to Mexico to help bridge that country's immediate pandemic vaccine requirements. This is not a donation. Mexico will replenish Canada's H1N1 vaccine supply by March 31, 2010.

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Canada Loans 5M Doses Of H1N1 Vaccine To Mexico PDF Print E-mail
Saturday, 09 January 2010 06:17

Canadian Health Minister Leona Aglukkaq on Wednesday announced plans for the country to loan Mexico five million doses of the H1N1 (swine flu) vaccine, Agence France-Presse reports. The loan will help Mexico meet its innoculation demand, while the country waits for H1N1 vaccine orders to be fulfilled by several manufacturers. "Mexico is expected to replenish the borrowed Canadian stock by the end of March, Aglukkaq said," according to the news service (1/6).

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Insect cells provide the key to alternative swine flu vaccination PDF Print E-mail
Tuesday, 05 January 2010 06:02

Scientists in Vienna have developed a new technique for producing vaccines for H1N1, 'swine flu', based on insect cells. The research, published today in the Biotechnology Journal, reveals how influenza vaccines can be produced faster than through the traditional method of egg-based production, revealing a new strategy for the fight against influenza pandemics.

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More H1N1 Vaccines Available In U.S., Many Americans Don't Want It PDF Print E-mail
Thursday, 31 December 2009 06:10

While an increasing number of H1N1 (swine flu) vaccines are available in the U.S., "more than half of American adults say they still don't want it, and one-third of parents say they don't want their children to get it either, according to two surveys," the Washington Post reports. "As of this week, 111 million doses of vaccine against the pandemic strain of H1N1 flu have been released to states and cities. Not all have been used. There have been no unusual or unexpected vaccine side effects reported"

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Calming The Public's Fears About The Pediatic H1N1 Vaccine Recall PDF Print E-mail
Thursday, 24 December 2009 04:24
There is no danger if your child received the H1N1 vaccine that was recalled by Sanofi Pasteur. That is the information being provided to anyone calling the NJ Poison Control Center's hotline, according to Bruce Ruck, Pharm.D., Director of Drug Information and Professional Education. The public should be reassured that this recall took place because specific lots were found to be slightly weaker than they should have been.
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Three Studies On H1N1 Vaccine Effectiveness And Safety Report That One Dose Is Needed For Adults And Two For Children PDF Print E-mail
Wednesday, 16 December 2009 23:17
Three articles published Online First and in an upcoming edition of The Lancet report the conclusions of three studies from the USA, China, and Hungary. They show that one dose of H1N1 influenza vaccine should give adults sufficient protection from infection. Two doses could be required for children aged under 9 years in the USA study or under 12 years for the Chinese study.
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