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Mimicking living cells: Synthesizing ribosomes PDF Print E-mail
Sunday, 30 June 2013 15:01

Synthetic biology technology could lead to new antibiotics, modified protein-generators

Synthetic biology researchers at Northwestern University, working with partners at Harvard Medical School, have for the first time synthesized ribosomes -- cell structures responsible for generating all proteins and enzymes in our bodies -- from scratch in a test tube.

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New trial model unlocks power of personalized medicine PDF Print E-mail
Wednesday, 07 December 2011 17:47
Oncology clinicians may soon have hundreds of biomarker tests available to them to assist in developing personalized cancer treatments, but some healthcare professionals believe that novel funding approaches for biomarker tests’ studies—a systematic process to move biomarker tests through regulatory agencies and a body of evidence supporting biomarker tests’ benefits—will all be necessary before healthcare system stakeholders accept their use.
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Manchester's 'first step' to perfect drug combinations PDF Print E-mail
Sunday, 23 October 2011 23:59

The researchers found a way of identifying ideal drug combinations from billions of others which would prevent inflammation from occurring.

The findings, published in Nature Chemical Biology, could be the first step in the development of new drug combinations to combat severe diseases and conditions.

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Young Genes Correlated With Evolution Of Human Brain PDF Print E-mail
Thursday, 20 October 2011 00:10

20111020rfsp01Young genes that appeared since the primate branch split from other mammal species are expressed in unique structures of the developing human brain, a new analysis finds.

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Cells Are Crawling All Over Our Bodies, But How? PDF Print E-mail
Thursday, 20 October 2011 00:04

For better and for worse, human health depends on a cell's motility –– the ability to crawl from place to place.

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New Gene Therapy Methods Accurately Correct Mutation In Patient's Stem Cells, Bringing Personalized Cell Therapies One Step Closer PDF Print E-mail
Saturday, 15 October 2011 01:14
For the first time, scientists have cleanly corrected a human gene mutation in a patient's stem cells. The result, reported in Nature, brings the possibility of patient-specific therapies closer to becoming a reality.
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How the Zebra Gets Its Stripes: A Simple Genetic Circuit PDF Print E-mail
Saturday, 15 October 2011 00:50

20111015rfsp02Many living things have stripes, but the developmental processes that create these and other patterns are complex and difficult to untangle.

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Improving Gene Therapy for Heart Disease, Cancer PDF Print E-mail
Thursday, 13 October 2011 05:58

20111013rfsp02A Loyola University Chicago Stritch School of Medicine study could lead to improved gene therapies for conditions such as heart disease and cancer as well as more effective vaccines for tuberculosis, malaria and other diseases.

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Scientists Move Closer to Predicting Who Will and Will Not Fight Off Severe Infections PDF Print E-mail
Thursday, 13 October 2011 05:09

Why are some people prone to severe infections, while others handle them with less difficulty? A new research report appearing online in the FASEB Journal attempts to answer this question by shedding light on the genetic differences that influence our ability to fight off bacterial infections.

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Improved Method for Detecting Mutant DNAs PDF Print E-mail
Tuesday, 11 October 2011 18:01

20111011rfsp02Molecular DNA testing methods offer clinicians powerful tools that serve to confirm or identify disease diagnoses.

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Researchers reveal ways to make personalized cancer therapies more cost effective PDF Print E-mail
Sunday, 11 March 2012 01:53

AURORA, Colo. -- As scientists continue making breakthroughs in personalized cancer treatment, delivering those therapies in the most cost effective manner has become increasingly important. Now researchers at the University of Colorado School of Medicine have identified new ways of doing just that, allowing more patients to benefit from this revolution in cancer care.

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UPMC to Build $300M Center for 'Innovative' Biomedical Science PDF Print E-mail
Friday, 28 October 2011 00:32
The University of Pittsburgh Medical Center said today that it plans to invest $294 million in building a research center in Pittsburgh that will focus on personalized medicine and the biology of cancer and aging.
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Good Start Genetics? Announces Validation Results For Its Next-Generation DNA Sequencing Platform For Genetic Disorder Carrier Screening PDF Print E-mail
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Thursday, 20 October 2011 00:14
Good Start Genetics, an innovative molecular diagnostics company developing the new gold standard for routine carrier screening in clinical practice, will announce later today positive results of a validation study of its proprietary next-generation DNA sequencing platform.
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UGA Scientists Team Up To Define First-Ever Sequence Of Biologically Important Carbohydrate PDF Print E-mail
Thursday, 20 October 2011 00:06

If genes provide the blueprint for life and proteins are the machines that do much of the work for cells, then carbohydrates that are linked to proteins are among the tools that enable cells to communicate with the outside world and each other.

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First-Ever Sequence and Structure of Biologically Important Carbohydrate PDF Print E-mail
Tuesday, 18 October 2011 16:48

If genes provide the blueprint for life and proteins are the machines that do much of the work for cells, then carbohydrates that are linked to proteins are among the tools that enable cells to communicate with the outside world and each other.

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Cells Have Early-Warning System for Intruders PDF Print E-mail
Saturday, 15 October 2011 00:54

20111015rfsp03When a thief breaks into a bank vault, sensors are activated and the alarm is raised. Cells have their own early-warning system for intruders, and scientists at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have discovered how a particular protein sounds that alarm when it detects invading viruses.

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From Blue Whales to Earthworms, a Common Mechanism Gives Shape to Living Beings PDF Print E-mail
Saturday, 15 October 2011 00:36

20111015rfsp01Why don't our arms grow from the middle of our bodies? The question isn't as trivial as it appears. Vertebrae, limbs, ribs, tailbone ... in only two days, all these elements take their place in the embryo, in the right spot and with the precision of a Swiss watch.

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'Dark Matter' of the Genome Revealed Through Analysis of 29 Mammals PDF Print E-mail
Thursday, 13 October 2011 05:31

20111013rfsp01An international team of researchers has discovered the vast majority of the so-called "dark matter" in the human genome, by means of a sweeping comparison of 29 mammalian genomes.

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Family History May Have More Important Role Than Previously Thought in Development of Alzheimer Disease PDF Print E-mail
Tuesday, 11 October 2011 18:16

20111011rfsp03Family history of Alzheimer disease is associated with several age-related changes that appear to influence Alzheimer disease (AD) biomarker abnormalities beyond the increased risk of the APOE4 gene, according to a report published in the October issue of Archives of Neurology, one of the JAMA/Archives journals.

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New Discovery Could Change the Face of Cell-Biology Research PDF Print E-mail
Tuesday, 11 October 2011 17:59

Rewrite the textbooks and revisit old experiments, because there's a new cog in our cellular machinery that has been discovered by researchers from the University of Alberta and the University of Cambridge Institute for Medical Research.

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