Mechanism explains how virus survives in the liver and how a new antiviral works

Chapel Hill, NC – Viral diseases are still one of the biggest challenges to medical science. Thanks to thousands of years of co-evolution with humans, their ability to harness the biology of their human hosts to survive and thrive makes them very difficult to target with medical treatment.

Researchers have identified what they claim is a fifth adaptor protein complex involved in shuttling cellular cargo from one organelle to another. They say that the complex, which they’ve designated AP-5, localizes to a late endosomal compartment, and its subunits can be found in all five eukaryotic supergroups.

Sistemic, the cell characterisation problem-solving service provider that uses miRNA, is a strong advocate for the potential of regenerative medicine. Dr Verna McErlane, Sistemic's Director of Commercial Operations, recently took part in a round-table discussion with leading stem cell researchers http://www.sistemic.co.uk/publications.

MiR-548d may play a super-regulatory role in pancreatic cancer, affecting multiple components of the signaling pathways associated with the disease, a recent study by Hannover Medical School researchers has reported.

Santaris Pharma is set to release new clinical data results from the miravirsen Phase 2a study to treat Hepatitis C virus (HCV) infected patients at the American Association for the Study of Liver Diseases (AASLD) 2011 annual meeting.