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Infectious Disease
HIV/AIDS Funding, Treatment Standards, Empowering Women Addressed At ICAAP PDF Print E-mail
Friday, 14 August 2009 04:16

Funding to fight the spread of HIV/AIDS in Asia and the Pacific has fallen short of the demand, and the majority of available money has missed reaching those at highest risk -- Swarup Sarkar, director of Asia unit for the Global Fund to Fight AIDS, Tuberculosis and Malaria -- said during a session at the 9th International Congress on AIDS in Asia and the Pacific (ICAAP) in Bali, Indonesia, the Jakarta Post reports. "More than 80 percent of the available budget has gone to low-risk young people, compared with less than 20 percent that has gone to high-risk young people," he said (Maulia, 8/13).

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The Secrets Of Ulcer-Causing Bacteria Revealed PDF Print E-mail
Friday, 14 August 2009 04:05
A team of researchers from Boston University, Harvard Medical School and Massachusetts Institute of Technology recently made a discovery that changes a long held paradigm about how bacteria move through soft gels. They showed that the bacterium that causes human stomach ulcers uses a clever biochemical strategy to alter the physical properties of its environment, allowing it to move and survive and further colonize its host.
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Low Prevalence Of HPV Infection May Be Tied To Poor Prognosis For Blacks With Head And Neck Cancer PDF Print E-mail
Wednesday, 12 August 2009 06:13

Researchers at the University of Maryland Marlene and Stewart Greenebaum Cancer have found that head and neck cancer patients who test positive for the human papillomavirus (HPV) have much better survival rates than patients who don't have the virus, according to a new study in the journal Cancer Prevention Research. The researchers also discovered that blacks in the study had a very low rate of HPV infection, and consequently worse survival, which may explain why African-American patients traditionally have had a poor prognosis for head and neck cancer.

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New Method For Neonatal ICUs Reduces Infection And Lung Distress In Premature Infants PDF Print E-mail
Wednesday, 12 August 2009 06:09

A new method for improving quality of care can reduce hospital-acquired infections and chronic respiratory distress with oxygen dependency in premature infants in neonatal ICUs, according to a new study in CMAJ (Canadian Medical Association Journal). The researchers developed the Evidence-based Practice for Improving Quality method and applied it to 12 Canadian Neonatal Network hospitals over a 3-year period. Working in multidisciplinary groups, each hospital developed a list of hospital-specific practice changes and priorities to implement in the neonatal ICU.

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First Human Gets New Antibody Aimed At Hepatitis C Virus PDF Print E-mail
Monday, 10 August 2009 05:50

Building upon a series of successful preclinical studies, researchers at MassBiologics of the University of Massachusetts Medical School (UMMS) today announced the beginning of a Phase 1 clinical trial, testing the safety and activity of a human monoclonal antibody they developed that can neutralize the Hepatitis C virus (HCV).

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Ambitious New Strategies Proposed For AIDS Vaccine Research PDF Print E-mail
Sunday, 09 August 2009 22:43

Researchers at the Yerkes National Primate Research Center, Emory University, believe conventional vaccine strategies should not be the only avenue explored in the development of an effective AIDS vaccine. Based on studying simian immunodeficiency viruses (SIVs) in African nonhuman primates, they propose an additional new approach to the AIDS vaccine research agenda in a commentary featured in the August issue of Nature Medicine. Their recommendations outline specific research priorities and describe how each may lead to a novel "out of the box" approach for developing an AIDS vaccine.

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Key To Strengthening Immune Response To Chronic Infection Found PDF Print E-mail
Friday, 07 August 2009 06:32

A team of researchers from The Wistar Institute has identified a protein that could serve as a target for reprogramming immune system cells exhausted by exposure to chronic viral infection into more effective "soldiers" against certain viruses like HIV, hepatitis C, and hepatitis B, as well as some cancers, such as melanoma.

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Structure Of Antibiotic Ramoplanin Reveals Promising Mechanism PDF Print E-mail
Wednesday, 05 August 2009 05:02

With the "last resort" antibiotic Vancomycin now plagued by the first signs of bacterial resistance, a scientific collaboration centered at Duke University has identified how a candidate successor antibiotic known as Ramoplanin A2 can kill pathogenic bacteria by interrupting how they form their cell membranes.

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Drug-resistant Malaria Has Emerged In Cambodia PDF Print E-mail
Tuesday, 04 August 2009 01:30

Malaria parasites in western Cambodia have become resistant to artemisinin-based therapies, the first-line treatment for malaria, according to a study published in the New England Journal of Medicine on July 29. Resistance to the drugs makes them less effective and could eventually render them obsolete, putting millions of lives at risk.

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Tiny Device To 'Sniff Out' Disease, Heart Attacks, Poison And Environmental Pollution Developed PDF Print E-mail
Monday, 03 August 2009 23:00

Like the sensitive seismographs that can pick up tremors of impending earthquakes long before they strike, a similar invention from Tel Aviv University researchers may change the face of molecular biology.

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Clostridium Difficile Infection: Tracking A Virulent Pathogen PDF Print E-mail
Friday, 14 August 2009 04:12
The rates and severity of Clostridium difficile infection (CDI) may be impacted by several factors, including antimicrobial use, other drug-prescribing factors, infection control practices, and the presence of a new strain of C. difficile that is more resistant to fluoroquinolones and associated with higher rates of morbidity and mortality. It is crucial for healthcare professionals to be aware of these factors and apply evidence-based practices for the prevention, diagnosis, and treatment of CDI.
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New Drug-resistant TB Strains Could Become Widespread, Says New Study PDF Print E-mail
Wednesday, 12 August 2009 06:17

The emergence of new forms of tuberculosis could swell the proportion of drug-resistant cases globally, a new study has found. The finding raises concern that although TB incidence is falling in many regions, the emergence of antibiotic resistance could see virtually untreatable strains of the disease become widespread.

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Misuse Of Common Antibiotic Is Creating Resistant TB PDF Print E-mail
Wednesday, 12 August 2009 06:12

Use of a common antibiotic may be undercutting its utility as a first-line defense against drug-resistant tuberculosis (TB). Fluoroquinolones are the most commonly prescribed class of antibiotics in the U.S. and are used to fight a number of different infections such as sinusitis and pneumonia. They are also an effective first line of defense against TB infections that show drug resistance. New research shows, however, that widespread general use of fluoroquinolones may be creating a strain of fluoroquinolone-resistant TB.

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Hepatitis Healing Power Of Blueberry Leaves PDF Print E-mail
Monday, 10 August 2009 05:53

A chemical found in blueberry leaves has shown a strong effect in blocking the replication of the Hepatitis C virus, opening up a new avenue for treating chronic HCV infections, which affect 200 million people worldwide and can eventually lead to cirrhosis and liver cancer.

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Current Hepatitis C Treatments Work Equally Well, Researchers Repor PDF Print E-mail
Monday, 10 August 2009 05:46

The three treatment combinations for clearing the most common form of the hepatitis C virus work equally well with similar side effects, UT Southwestern Medical Center researchers and their colleagues in 13 other institutions have found. Hepatitis C affects nearly 4 million Americans and leads to cirrhosis and liver cancer but can be arrested permanently in many patients.

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Why Even Treated Genital Herpes Sores Boost The Risk Of HIV Infection PDF Print E-mail
Friday, 07 August 2009 06:34

New research helps explain why infection with herpes simplex virus-2 (HSV-2), which causes genital herpes, increases the risk for HIV infection even after successful treatment heals the genital skin sores and breaks that often result from HSV-2.

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Study links selection for pathogen-resistance with increased risk for inflammatory disease PDF Print E-mail
Friday, 07 August 2009 04:54

New research reveals that a simple laboratory assay detects a genetic variation in host response to bacterial infection that is associated with an increased susceptibility for inflammatory disease. The study, published by Cell Press online on August 6th in the American Journal of Human Genetics, also provides fascinating insight into the link between evolution and the ability to ward off pathogens.

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Cannibalistic Cells May Help Prevent Infections PDF Print E-mail
Wednesday, 05 August 2009 04:52

Infectious-disease specialists at UT Southwestern Medical Center have demonstrated that a cannibalistic process in cells plays a key role in limiting Salmonella infection.

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Tuberculosis Drugs Under Development Expected To Have Major Impact On The Disease PDF Print E-mail
Monday, 03 August 2009 23:07

The latest drug regimens, vaccines and diagnostic tools under development to combat tuberculosis could have a potentially large impact on the disease once they become available, according to research findings published in the Aug. 3 early edition online of the Proceedings of the National Academy of Sciences.

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Virus Linked To Some Cases Of Common Skin Cancer PDF Print E-mail
Monday, 03 August 2009 09:02

A virus discovered last year in a rare form of skin cancer has also been found in people with the second most common form of skin cancer among Americans, according to researchers at the Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute.

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