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Genomics & Proteomics
Johns Hopkins Researchers Discover How Some Breast Cancers Alter Their Sensitivity To Estrogen PDF Print E-mail
Friday, 29 July 2011 00:50

Using human breast cancer cells and the protein that causes fireflies to glow, a Johns Hopkins team has shed light on why some breast cancer cells become resistant to the anticancer effects of the drug tamoxifen.

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Convergence In Head And Neck Cancer --Centers Collaborate To Reveal Unexpected Genetic Mutations PDF Print E-mail
Friday, 29 July 2011 00:41
20110729rfgp01Powerful new technologies that zoom in on the connections between human genes and diseases have illuminated the landscape of cancer, singling out changes in tumor DNA that drive the development of certain types of malignancies such as melanoma or ovarian cancer.
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Eliminating Protein In Specific Brain Cells Blocks Nicotine Reward PDF Print E-mail
Wednesday, 27 July 2011 02:49

20110727rfgp02Removing a protein from cells located in the brain's reward center blocks the anxiety-reducing and rewarding effects of nicotine, according to a new animal study in the July 27 issue of The Journal of Neuroscience.

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Study Sheds Light On Role Of Genetics In Eating Disorders PDF Print E-mail
Wednesday, 27 July 2011 02:42

A substantial number of people with eating disorders, such as anorexia nervosa have a chronic course. They are severely underweight and have a high likelihood of dying from malnutrition.

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Life Scientists Use Novel Technique To Produce Genetic Map For African Americans PDF Print E-mail
Monday, 25 July 2011 04:07

20110725rfgp03UCLA life scientists and colleagues have produced one of the first high-resolution genetic maps for African American populations.

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Predicting Second Cancers After Radiation For Children With Hodgkin Lymphoma PDF Print E-mail
Monday, 25 July 2011 03:35

20110725rfgp01A genome-wide association study published in the August issue of Nature Medicine has found two tiny genetic variations that can predict which patients with Hodgkin's lymphoma are most likely to develop radiation-induced second cancers years after treatment.

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Chromosome Number Changes In Yeast PDF Print E-mail
Friday, 22 July 2011 04:22
20110722rfgp02Researchers from Trinity College Dublin have uncovered the evolutionary mechanisms that have caused increases or decreases in the numbers of chromosomes in a group of yeast species during the last 100-150 million years.
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Sperm Coat Protein May Be Key To Male Infertility PDF Print E-mail
Friday, 22 July 2011 04:14

20110722rfgpns01The loss of a protein that coats sperm may explain a significant proportion of infertility in men worldwide, according to a study by an international team of researchers led by UC Davis.

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Researchers Able To Precisely Simulate The Inhibition Of Genes With New Cancer Drugs PDF Print E-mail
Wednesday, 20 July 2011 18:54
20110720rfgp03Only one in twenty cancer drugs makes its way from the laboratory to become an approved pharmaceutical product.
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Newly Developed Fluorescent Protein Makes Internal Organs Visible PDF Print E-mail
Wednesday, 20 July 2011 18:29

20110720rfgp01Researchers at Albert Einstein College of Medicine of Yeshiva University have developed the first fluorescent protein that enables scientists to clearly "see" the internal organs of living animals without the need for a scalpel or imaging techniques that can have side effects or increase radiation exposure.

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A Closer Look At Cells PDF Print E-mail
Friday, 29 July 2011 00:45

Many substances and nutrients are exchanged across the cell membrane. EPFL scientists have developed a method to observe these exchanges, by taking a highly accurate count of the number of proteins found there. Their research has just been published in the Journal Plos One.

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New Strategy Developed To Uncover Structural Variations Of Human Genomes PDF Print E-mail
Wednesday, 27 July 2011 02:52
20110727rfgp03The study on single-nucleotide resolution structural variations (SVs) of an Asian and African genome was published online in Nature Biotechnology.
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Discovery Of Elusive Gene That Makes Platelets Grey PDF Print E-mail
Wednesday, 27 July 2011 02:45

20110727rfgp01Researchers have identified an elusive gene responsible for Grey Platelet Syndrome, an extremely rare blood disorder in which only about 50 known cases have been reported. As a result, it is hoped that future cases will be easier to diagnose with a DNA test.

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DNA Sequencing Technique Using Semiconductors Developed - Low Cost, Portable And Scalable PDF Print E-mail
Monday, 25 July 2011 04:13
Scientists at Ion Torrent Systems Inc. have created a DNA sequencing technique using semiconductors instead of the costly and complex optical technology.
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DNA Helps Glucose Meters Measure More Than Sugar - Medical Diagnostics And Environmental Monitoring PDF Print E-mail
Monday, 25 July 2011 03:59
20110725rfgp02Glucose meters aren't just for diabetics anymore. Thanks to University of Illinois chemists, they can be used as simple, portable, inexpensive meters for a number of target molecules in blood, serum, water or food.
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Seventh And Eighth Bases Of DNA Identified By UNC Researchers PDF Print E-mail
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Friday, 22 July 2011 04:26
For decades, scientists have known that DNA consists of four basic units - adenine, guanine, thymine and cytosine.
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Complex Proteins In 3D Thanks To Simple Heat-Loving Fungus PDF Print E-mail
Friday, 22 July 2011 04:18
A fungus that lives at extremely high temperatures could help understand structures within our own cells.
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Tumor Suppressor Protein Is A Key Regulator Of Immune Response And Balance PDF Print E-mail
Wednesday, 20 July 2011 19:04
St. Jude Children's Research Hospital scientists have identified a key immune system regulator, a protein that serves as a gatekeeper in the white blood cells that produce the "troops" to battle specific infections.
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‘Cord-Stopper’ Protein Complex Makes Chromosomes Easier To Move PDF Print E-mail
Wednesday, 20 July 2011 18:35

20110720rfgp02As any rock-climber knows, trailing a long length of rope behind you is not easy. A dangling length of rope is unwieldy and hard to manoeuvre, and can get tangled up or stuck on an outcropping.

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Deeper Insight Into Gene Regulation Will Be Provided By Novel DNA Sequencer For MDC's Systems Biology PDF Print E-mail
Monday, 18 July 2011 03:24
The Berlin Institute for Medical Systems Biology (BIMSB) of the Max Delbrück Center for Molecular Medicine (MDC) in Berlin, Germany, will be the first academic research institution in Continental Europe to acquire a novel DNA sequencer enabling the sequencing of single DNA molecules in real time.
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