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Genomics & Proteomics
Predicting Second Cancers After Radiation For Children With Hodgkin Lymphoma PDF Print E-mail
Monday, 25 July 2011 03:35

20110725rfgp01A genome-wide association study published in the August issue of Nature Medicine has found two tiny genetic variations that can predict which patients with Hodgkin's lymphoma are most likely to develop radiation-induced second cancers years after treatment.

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Chromosome Number Changes In Yeast PDF Print E-mail
Friday, 22 July 2011 04:22
20110722rfgp02Researchers from Trinity College Dublin have uncovered the evolutionary mechanisms that have caused increases or decreases in the numbers of chromosomes in a group of yeast species during the last 100-150 million years.
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Sperm Coat Protein May Be Key To Male Infertility PDF Print E-mail
Friday, 22 July 2011 04:14

20110722rfgpns01The loss of a protein that coats sperm may explain a significant proportion of infertility in men worldwide, according to a study by an international team of researchers led by UC Davis.

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Researchers Able To Precisely Simulate The Inhibition Of Genes With New Cancer Drugs PDF Print E-mail
Wednesday, 20 July 2011 18:54
20110720rfgp03Only one in twenty cancer drugs makes its way from the laboratory to become an approved pharmaceutical product.
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Newly Developed Fluorescent Protein Makes Internal Organs Visible PDF Print E-mail
Wednesday, 20 July 2011 18:29

20110720rfgp01Researchers at Albert Einstein College of Medicine of Yeshiva University have developed the first fluorescent protein that enables scientists to clearly "see" the internal organs of living animals without the need for a scalpel or imaging techniques that can have side effects or increase radiation exposure.

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Discovery Of New Gene For Intellectual Disability PDF Print E-mail
Monday, 18 July 2011 03:20
20110718rfgp03A gene linked to intellectual disability was found in a study involving the Centre for Addiction and Mental Health (CAMH) - a discovery that was greatly accelerated by international collaboration and new genetic sequencing technology, which is now being used at CAMH.
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Parkinson's Disease: Mutation In VPS35 Gene Linked To Late-Onset PDF Print E-mail
Monday, 18 July 2011 03:07
20110718rfgp01Using the latest technology in genetic research, a Canadian-led study found a mutation in a gene called VPS35 causes late-onset Parkinson's disease.
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'Unnatural' Chemical Allows Salk Researchers To Watch Protein Action In Brain Cells PDF Print E-mail
Friday, 08 July 2011 23:24
Researchers at the Salk Institute have been able to genetically incorporate "unnatural" amino acids, such as those emitting green fluorescence, into neural stem cells, which then differentiate into brain neurons with the incandescent "tag" intact.
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During Development Early Embryos Can Correct Genetic Abnormalities PDF Print E-mail
Wednesday, 06 July 2011 05:00

20110706rfgp02Professor William G. Kearns told the annual meeting of the European Society of Human Reproduction and Embryology that a three-day-old embryo (called a cleavage stage embryo) with an incorrect number of chromosomes (known as "aneuploidy") was capable of undergoing "a dynamic process of genetic normalisation" so that by day five, when it had developed to the blastocyst stage, it had become euploid, with the correct number of chromosomes.

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A Chaperone System Guides Tail-Anchored Membrane Proteins To Their Destined Membrane PDF Print E-mail
Wednesday, 06 July 2011 04:56
A newly synthesized protein is as fragile as a newborn baby. It could never fold into its correct three dimensional structure if it was not protected by chaperones within the densely populated cytosol.
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Seventh And Eighth Bases Of DNA Identified By UNC Researchers PDF Print E-mail
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Friday, 22 July 2011 04:26
For decades, scientists have known that DNA consists of four basic units - adenine, guanine, thymine and cytosine.
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Complex Proteins In 3D Thanks To Simple Heat-Loving Fungus PDF Print E-mail
Friday, 22 July 2011 04:18
A fungus that lives at extremely high temperatures could help understand structures within our own cells.
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Tumor Suppressor Protein Is A Key Regulator Of Immune Response And Balance PDF Print E-mail
Wednesday, 20 July 2011 19:04
St. Jude Children's Research Hospital scientists have identified a key immune system regulator, a protein that serves as a gatekeeper in the white blood cells that produce the "troops" to battle specific infections.
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‘Cord-Stopper’ Protein Complex Makes Chromosomes Easier To Move PDF Print E-mail
Wednesday, 20 July 2011 18:35

20110720rfgp02As any rock-climber knows, trailing a long length of rope behind you is not easy. A dangling length of rope is unwieldy and hard to manoeuvre, and can get tangled up or stuck on an outcropping.

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Deeper Insight Into Gene Regulation Will Be Provided By Novel DNA Sequencer For MDC's Systems Biology PDF Print E-mail
Monday, 18 July 2011 03:24
The Berlin Institute for Medical Systems Biology (BIMSB) of the Max Delbrück Center for Molecular Medicine (MDC) in Berlin, Germany, will be the first academic research institution in Continental Europe to acquire a novel DNA sequencer enabling the sequencing of single DNA molecules in real time.
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A New Gene Identified For Restless Legs Syndrome PDF Print E-mail
Monday, 18 July 2011 03:10

20110718rfgp02People suffering from restless legs syndrome (RLS) experience unpleasant sensations in the legs at night for which the only remedy is movement.

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Research Team Finds Similarities In Genomes Across Multiple Species PDF Print E-mail
Friday, 08 July 2011 23:52

By mapping various genomes onto an X-Y axis, a team comprised mostly of Kansas State University researchers has found that Charles Darwin and a fruit fly - among other organisms - have a lot in common genetically.

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Mediator MED26 Shifts An Idling Polymerase Into High Gear In The Control Of Gene Expression PDF Print E-mail
Friday, 08 July 2011 23:22

Look up "transcription" - the copying of a gene's DNA into RNA intermediaries - in any old molecular biology text book, and it all seems very simple: RNA polymerase II, the enzyme that catalyzes the reaction, assembles at the start site and starts motoring down the strand, cranking out the RNA ribbon used to construct proteins.

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DNA Sequenced Of Cancer-Resistant Rodent PDF Print E-mail
Wednesday, 06 July 2011 04:57
20110706rfgp01The naked mole-rat is native to the deserts of East Africa and has unique physical traits that allow it to survive in harsh environments for many years.
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Lifestyle, Diet Can Significantly Influence Course Of Macular Degeneration Among Individuals With The Same Genetic Susceptibility PDF Print E-mail
Wednesday, 06 July 2011 04:54
Eating a diet high in vitamin D, as well as the nutrients betaine and methionine, might help reduce the risk of macular degeneration, according to new research conducted by Tufts Medical Center scientists.
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