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Genomics & Proteomics
Human Development Is Set By Ongoing Interplay Of Parent And Offspring Genes, Analysis Suggests PDF Print E-mail
Wednesday, 29 July 2009 03:51
An analysis of rare genetic disorders in which children lack some genes from one parent suggests that maternal and paternal genes engage in a subtle tug-of-war well into childhood, and possibly as late as the onset of puberty.
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MicroParticle Proteomics Licenses Cardio Disease Biomarker from UVA Patent Foundation PDF Print E-mail
Wednesday, 29 July 2009 03:42

MicroParticle Proteomics said last week that it has exclusively licensed a blood-based biomarker from the University of Virginia Patent Foundation that could serve as the basis for diagnostic and prognostic tests for cardiovascular disease and ischemic heart failure.

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The 15-Minute Genome: Faster, Cheaper Genome Sequencing On The Way PDF Print E-mail
Tuesday, 28 July 2009 02:39

In the race for faster, cheaper ways to read human genomes, Pacific Biosciences is hoping to set a new benchmark with technology that watches DNA being copied in real time. The device is being developed to sequence DNA at speeds 20,000 times faster than second-generation sequencers currently on the market and will ultimately have a price tag of $100 per genome.

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Researchers rapidly turn bacteria into biotech factories PDF Print E-mail
Monday, 27 July 2009 04:20
High-throughput sequencing has turned biologists into voracious genome readers, enabling them to scan millions of DNA letters, or bases, per hour. When revising a genome, however, they struggle, suffering from serious writer's block, exacerbated by outdated cell programming technology. Labs get bogged down with particular DNA sentences, tinkering at times with subsections of a single gene ad nauseam before moving along to the next one.
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Mutation Causing One Type Of Male Infertility Found PDF Print E-mail
Sunday, 26 July 2009 17:45

A genetic mutation that lies behind one type of male infertility has been discovered by researchers at Oxford University, Ghent University in Belgium, and the University of Massachusetts, Amherst in the USA.

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Unlocking Genetic Diversity of Rice PDF Print E-mail
Friday, 24 July 2009 06:17

By looking at what different types of rice have in common, a team of international scientists is unlocking rice’s genetic diversity to help conserve it and find valuable rice genes to help improve rice production.

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Horizon Discovery to Develop Drug Sensitivity Panel for DxS PDF Print E-mail
Wednesday, 22 July 2009 08:18
Horizon Discovery said today that it will develop a panel of human isogenic cell models of drug sensitivity and resistance mechanisms in cancer patients for DxS to use in its pharmacogenetic program.
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Korea's Genomic Medicine Institute Adds Seven Illumina Genome Analyzers PDF Print E-mail
Wednesday, 22 July 2009 08:06
Illumina said today that the Genomic Medicine Institute at Seoul National University College of Medicine in Korea has purchased seven Genome Analyzer IIx sequencers.
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SNPs in Non-Cancerous Tissue May Differ From Those In Blood, Study Finds PDF Print E-mail
Monday, 20 July 2009 06:14
NEW YORK-A new paper by Montreal researchers is providing evidence that the gene variants found in some non-cancerous tissues may differ from those present in blood samples from the same individual.
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Genomes of Parasitic Flatworms Decoded PDF Print E-mail
Monday, 20 July 2009 06:01
Two international research teams have determined the complete genetic sequences of two species of parasitic flatworms that cause schistosomiasis, a debilitating condition also known as snail fever. Schistosoma mansoni and Schistosoma japonicum are the first sequenced genomes of any organism in the large group called Lophotrochozoa, which includes other free-living and parasitic flatworms as well as segmented roundworms, such as the earthworm.
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MEK4, Genistein And Invasion Of Human Prostate Cancer Cells PDF Print E-mail
Wednesday, 29 July 2009 03:47

Researchers have identified MEK4 as a pro-invasion protein and the target for genistein, a dietary compound, in prostate cancer cells, according to a new study published online July 28 in the Journal of the National Cancer Institute.

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Mapping the crocodile genome PDF Print E-mail
Wednesday, 29 July 2009 03:02

The first ever genetic linkage map for a non-avian member of the Class Reptilia has been developed. Researchers writing in the open access journal BMC Genomics have constructed a first-generation genetic linkage map for the saltwater crocodile Crocodylus porosus.

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After Dinosaurs, Mammals Rise But Their Genomes Get Smaller PDF Print E-mail
Tuesday, 28 July 2009 02:38

Evidence buried in the chromosomes of animals and plants strongly suggests only one group -- mammals -- have seen their genomes shrink after the dinosaurs' extinction. What's more, that trend continues today, say Indiana University Bloomington scientists in the first issue of a new journal, Genome Biology and Evolution.

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NMR Study Recognizes Individual Metabolic Phenotypes PDF Print E-mail
Monday, 27 July 2009 03:04
An Italian and German research team has found evidence suggesting individual metabolic phenotypes differ from one individual to the next but are actually quite stable within each individual over time — a finding that they say might eventually open the door for personalized medical treatments based on metabolic profiling.
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Expression, Sequencing Study IDs Imprinted Pig Genes PDF Print E-mail
Friday, 24 July 2009 08:13
In a paper appearing online this month in the journal Biology of Reproduction, researchers from North Carolina State University and the US Department of Agriculture used a combination of gene expression and sequencing approaches to catalog imprinted genes in developing swine fetuses.
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Scientists Present First Genetic Evidence For Why Placebos Work PDF Print E-mail
Wednesday, 22 July 2009 08:21

Placebos are a sham — usually mere sugar pills designed to represent "no treatment" in a clinical treatment study. The effectiveness of the actual medication is compared with the placebo to determine if the medication works.

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Biomarkers Show Promise for Classifying Those at Alzheimer's Risk PDF Print E-mail
Wednesday, 22 July 2009 08:10

A trio of cerebrospinal fluid biomarkers can accurately classify individuals who will develop Alzheimer's disease, according to a paper in today's issue of the Journal of the American Medical Association.

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C. elegans Poster Award Recipients Announced By Genetics Society Of America PDF Print E-mail
Monday, 20 July 2009 06:25
The Genetics Society of America is pleased to announce the recipients for the first place poster awards from the 17th International C. elegans meeting held June 24-28 at the University of California, Los Angeles. Eighteen posters from among the 375 graduate posters reviewed by the selection committee were selected for the first award of $55 (US).
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Scientists Locate Disease Switches PDF Print E-mail
Monday, 20 July 2009 06:06

A team of scientists from the University of Copenhagen and the Max Planck Institute in Germany, using groundbreaking technology, has identified no less than 3,600 molecular switches in the human body.

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Mouse Transcriptome Study Offers Window into Developing Mammalian Brain PDF Print E-mail
Tuesday, 14 July 2009 08:55
Mammalian brain development involves the coordinated expression of a host of genes — including many transcriptional regulators, according to a study comparing the mouse cortex transcriptomes at two early developmental stages.
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