A specific gene variation in the prostate stem cell antigen (PSCA) gene causes a 30% to 40% higher risk for urinary bladder cancer, according to a scientific team led by The University of Texas M. D. Anderson Cancer Center. They say that the rs2294008 variant was associated consistently with the disease and was found to be the only common missense genetic variation in the PSCA gene region.

The new research field of synthetic biology will, in the medium term, open up a great deal of potential for combining novel genetic methods with engineering principles. This will facilitate the development, not only of new vaccines and medicines, but also of fuels and new materials.

Montreal, July 30, 2009 Patients with cystic fibrosis (CF) usually experience significant muscle loss, a symptom traditionally considered to be a secondary complication of the devastating genetic disease. However, a recent study by Dr. Basil Petrof reverses the equation: his results show that muscle atrophy and weakness may be a primary symptom caused by the effects of CFTR gene mutations on the muscle itself. Dr. Petrof's findings will be published on July 31 in Public Library of Science Genetics.

Researchers have identified MEK4 as a pro-invasion protein and the target for genistein, a dietary compound, in prostate cancer cells, according to a new study published online July 28 in the Journal of the National Cancer Institute.

The first ever genetic linkage map for a non-avian member of the Class Reptilia has been developed. Researchers writing in the open access journal BMC Genomics have constructed a first-generation genetic linkage map for the saltwater crocodile Crocodylus porosus.

Evidence buried in the chromosomes of animals and plants strongly suggests only one group -- mammals -- have seen their genomes shrink after the dinosaurs' extinction. What's more, that trend continues today, say Indiana University Bloomington scientists in the first issue of a new journal, Genome Biology and Evolution.