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Thursday, 13 August 2009 04:24 |
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 The smallest organisms to use a biological compass are magnetotactic bacteria, however mysteries remain about exactly how these bacteria create their cellular magnets. In a study published online in Genome Research, scientists have used genome sequencing to unlock new secrets about these magnetic microbes that could accelerate biotechnology and nanotechnology research.
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Wednesday, 12 August 2009 05:50 |
 Scientists from Stanford University reported online today in Nature Biotechnology that they have sequenced the genome of a Caucasian man using a Helicos Biosciences Heliscope single molecule sequencer. Stanford University bioengineer and Helicos Co-founder Stephen Quake, who now chairs the company's scientific advisory board, sequenced his own genome — using a single Heliscope machine and four data collection runs — with help from two members of his lab: graduate student Dmitry Pushkarev and research technical manager Norma Neff. |
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Wednesday, 12 August 2009 05:02 |
 The National Center for Genome Resources (NCGR) elected to use febit’s automated HybSelect™ DNA sequence capture technology for a gene resequencing program it hopes will ultimately lead to the development of tests for identifying recessive genetic diseases in prospective parents. Based on the Geniom RT Analyzer platform, the automated HybSelect technology will be used to capture specific exons of interest for resequencing using Illumina next-generation sequencing technology.
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Monday, 10 August 2009 06:10 |
New work by MIT cancer biologists shows that the interplay between two key genes that are often defective in tumors determines how cancer cells respond to chemotherapy.
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Monday, 10 August 2009 06:03 |
 Scientists have identified a genomic "signature" in circulating blood that reveals exposure to common upper respiratory viruses, like the cold or flu, even before symptoms appear. The tell-tale viral signature reflects a set of subtle but robust changes in genes that are activated as the body responds to infection. The signal from the signature is strong enough in symptomatic individuals to clearly reveal whether their infection is viral or bacterial. It can also discriminate between who has a viral infection and who does not - all from a single tube of blood.
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Friday, 07 August 2009 06:13 |
 An international research team has developed a new resource for mapping the genetics underlying complex traits in corn. |
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Friday, 07 August 2009 06:03 |
 A team of researchers from Pennsylvania State University has identified dozens of genes whose expression in rat brains changes in concert with drug relapse behavior in heroin-addicted animals. |
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Friday, 07 August 2009 05:55 |
 Computational biologists at Carnegie Mellon University have developed an analytical technique to detect the multiple genetic variations that contribute to complex disease syndromes such as diabetes, asthma and cancer, which are characterized by multiple clinical and molecular traits. |
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Wednesday, 05 August 2009 19:03 |
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 The structure of an entire HIV genome has been decoded for the first time by researchers at the University of North Carolina at Chapel Hill. The results have widespread implications for understanding the strategies that viruses, like the one that causes AIDS, use to infect humans.
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Wednesday, 05 August 2009 04:46 |
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 ANN ARBOR, Mich. As the body creates antibodies to fight invaders, a three-protein DNA repair complex called MRN is crucial for a normal gene-shuffling process to proceed properly, University of Michigan research shows.
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Wednesday, 12 August 2009 05:59 |
 British researchers reported this week that metabolic profiling of urine samples prior to drug treatment could help predict an individual's response to the drug."Even for this most familiar drug, pharmacometabonomic analysis will yield significantly increased understanding of its metabolic behavior in humans," the researchers wrote. "These findings have considerable implications for personalized drug treatment in general and lead to new and testable hypotheses for a number of diseases." |
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Wednesday, 12 August 2009 05:42 |
 Scripps Genomic Medicine will work with Scripps Memorial Hospital La Jolla to conduct genomic studies of women for known variants of breast cancer in order to correlate the presence of variants with diagnosis of the disease, Scripps Genomic Medicine said. The PINK study, which is funded by the Scripps Research Institute, aims to enroll 3,500 women who are receiving screenings at the Scripps Polster Breast Care Center who have had at least five years of breast imaging records available, and who will undergo a DNA analysis. |
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Monday, 10 August 2009 06:11 |
The Stowers Institute's Conaway Lab has uncovered a previously unknown function of a gene product called Amplified in Liver Cancer 1 (Alc1), which may play a role in the onset of cancer. The work is published in the Proceedings of the National Academy of Science Early Edition.
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Monday, 10 August 2009 06:08 |
 For her PhD thesis, the researcher studied the genetic profiles of 175 cases of patients suffering from celiac illness, in order to determine which genes are related to the disease and to study diagnostic methods.
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Monday, 10 August 2009 05:58 |
 Peering into the DNA of tiny yeast, researchers at the Moores Cancer Center at the University of California, San Diego and the San Diego Branch of the Ludwig Institute for Cancer Research have pinpointed a large number of genes that can prevent a type of genetic rearrangement that may lead to cancer and other diseases.
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Friday, 07 August 2009 06:06 |
 In a paper appearing online today in the New England Journal of Medicine, researchers from Washington University have published results from the second sequenced acute myeloid leukemia genome. |
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Friday, 07 August 2009 06:00 |
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As letters of the alphabet spell out words, when amino acids are linked to one another in a particular order they "spell out" proteins. But sometimes the cell machinery for building proteins in our bodies makes a mistake and the wrong amino acid is inserted. The consequences can be devastating, resulting in a garbled protein that no longer has the correct function, possibly leading to cancers and other diseases. |
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Wednesday, 05 August 2009 21:26 |
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 Decoding the complete DNA of cancer patients is giving scientists at Washington University School of Medicine in St. Louis a clearer picture of the complexity of the disease and allowing them to see intriguing and unexpected genetic relationships among patients.
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Wednesday, 05 August 2009 04:47 |
 Based on their phylogenetic analysis, an international research team has concluded that the human malaria parasite Plasmodium falciparum originated from P. reichenowi, a species carried by chimpanzees. |
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Wednesday, 05 August 2009 04:40 |
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 African village dogs are not a mixture of modern breeds but have directly descended from an ancestral pool of indigenous dogs, according to a Cornell-led genetic analysis of hundreds of semi-feral African village dogs.
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