Research Frontiers - eBioNews

Research Frontiers - eBioNews

Stem Cells

UCLA stem cell researchers move toward treatment for rare genetic nerve disease

U of M researchers discover link between heart, blood, and skeletal muscle

Stem cells enable personalised treatment for bleeding disorder

One of the key circuits in regulating genes involved in producing blood stem cells is deciphered

Temple scientists target DNA repair to eradicate leukemia stem cells

Stem cells develop best in 3D

Stanford/Yale study gives insight into subtle genomic differences among our own cells

Solving Stem Cell Mysteries

Stem cells from muscle tissue may hold key to cell therapies for neurodegenerative diseases

Discovery of Reprogramming Signature May Help Overcome Barriers to Stem Cell-Based Regenerative Medicine

>> More in: Stem Cells

RNAi & MicroRNA

Antisense Making Sense to Isis Partners

Alnylam Presents Preclinical Data from Hemophilia, Hemoglobinopathy Programs

Stanford researchers discover master regulator of skin development

Programmable RNA Complex Could Speed Genome Editing in the Lab

Short Stretches of piRNA Evaluate Cells’ Genetic History

BGI researchers uncover extensive RNA editing in a human transcriptome

Hepatitis C virus hijacks liver microRNA

New protocols improve detection of microRNAs for diagnosis

Roche RNAi Assets Go to Arrowhead

New Role for RNA Interference During Chromosomal Replication Discovered

>> More in: RNAi & MicroRNA

Neurosciences

Cocaine vaccine passes key testing hurdle

UCLA study shows that individual brain cells track where we are and how we move

Hitting ‘reset’ in protein synthesis restores myelination, suggests new treatment for misfolded protein diseases, such as CMT, Alzheimer’s

Breakthrough in neuroscience could help re-wire appetite control

Researchers discover new clues about how amyotrophic lateral sclerosis develops

New model could lead to improved treatment for early stage Alzheimer’s

Parkin protects from neuronal cell death

Neuronal activity induces tau release from healthy neurons

Novel herbal compound offers potential to prevent and treat Alzheimer's disease

Teaching the brain to speak again

>> More in: Neurosciences

Biomarkers & Drug Targets

Research reveals possible reason for cholesterol-drug side effects

Mapping of cancer cell fuel pumps paves the way for new drugs

UTSW researchers identify new potential target for cancer therapy

Key Bone Marrow Protein Identified as Potential New Leukemia Treatment Target

New metabolite-based diagnostic test could help detect pancreatic cancer early

New stroke gene discovery could lead to tailored treatments

The Most Important New Drug Of 2012

Steroid hormone receptor prefers working alone to shut off immune system genes

Investigational agent targets gene signaling pathways to improve response for patients with CLL

Cell surface transporters exploited for cancer drug delivery

>> More in: Biomarkers & Drug Targets

Genomics & Proteomics

The genome sequence of Tibetan antelope sheds new light on high-altitude adaptation

Sacred lotus genome sequence enlightens scientists

Genome study suggests new strategies for understanding and treating pulmonary fibrosis

The new age of proteomics: An integrative vision of the cellular world

When will genomic research translate into clinical care -- and at what cost?

The first goat genome sets a good example for facilitating de novo assembly of large genomes

Genes linked to low birth weight, adult shortness and later diabetes risk

Short DNA strands in the genome may be key to understanding human cognition and diseases

Skin cells reveal DNA's genetic mosaic

BUSM study investigates genetic variants' role in increasing Parkinson's disease risk

>> More in: Genomics & Proteomics

Systems Bio & Personalized Med

Researchers reveal ways to make personalized cancer therapies more cost effective

New trial model unlocks power of personalized medicine

UPMC to Build $300M Center for 'Innovative' Biomedical Science

Manchester's 'first step' to perfect drug combinations

Good Start Genetics? Announces Validation Results For Its Next-Generation DNA Sequencing Platform For Genetic Disorder Carrier Screening

Young Genes Correlated With Evolution Of Human Brain

UGA Scientists Team Up To Define First-Ever Sequence Of Biologically Important Carbohydrate

Cells Are Crawling All Over Our Bodies, But How?

First-Ever Sequence and Structure of Biologically Important Carbohydrate

New Gene Therapy Methods Accurately Correct Mutation In Patient's Stem Cells, Bringing Personalized Cell Therapies One Step Closer

>> More in: Systems Bio & Personalized Med, Systems Bio & Personalized Med

Cancer Research

Study finds gaps in 'decision aids' designed to help determine right cancer screening option

CU study suggests link between tumor suppressors and starvation survival

CWRU School of Medicine researchers discover new target for personalized cancer therapy

How does pregnancy reduce breast cancer risk?

GW Cancer Institute Publishes Research on Challenges Faced by Adolescent and Young Adult Cancer Survivors

Physicists, biologists unite to expose how cancer spreads

Battery of tests on cancer cells shows them as 'squishy,' yet tactically strong

Commonly used drug can limit radiation damage to lungs and heart for cancer patients

2 landmark studies report on success of using image-guided brachytherapy to treat cervical cancer

Same protein that fires up cancer-promoting Erk also blocks its activation

>> More in: Cancer Research

Bio-Chip & Nanotechnology

Penn Researchers attach Lyme disease antibodies to nanotubes, paving way for diagnostic device

Scientists discover that shape matters in DNA nanoparticle therapy

Researchers develop method to grow artificial tissues with embedded nanoscale sensors

Nanoparticles engineered at Notre Dame promise to improve blood cancer treatment

Nano-Devices that Cross Blood-Brain Barrier Open Door to Treatment of Cerebral Palsy, Other Neurologic Disorders

Stanford-spawned nanoparticles home in on brain tumors, boost accuracy of surgical removal

A shiny new tool for imaging biomolecules

Targeted method improves treatment of brain cancers

Nanopills release drugs directly from the inside of cells

Getting Cancer Cells to Swallow Poison: Nanotechnology Researchers Develop New Strategy to Deliver Chemotherapy to Prostate Cancer Cells

>> More in: Bio-Chip & Nanotechnology

Infectious Disease

Making Vaccines from Parts

New malaria test kit gives a boost to elimination efforts worldwide

Potential flu pandemic lurks

The risks of H7N9 infection mapped

Antibody evolution could guide HIV vaccine development

New vaccine-design approach targets HIV and other fast-mutating viruses

Pitt team finds immunity protein that ramps up inflammation, and agents that can block it

New study identifies unique mechanisms of antibiotic resistance

'Defective' virus surprisingly plays major role in spread of disease, UCLA life scientists report

Sustained virological response linked with improved survival for patients with chronic HCV infection

>> More in: Infectious Disease

Biomedical Imaging

Breathe in, breathe out: New way of imaging lungs could improve COPD diagnosis and treatment

Non-invasive imaging can detect mutations within a brain tumor

Penn engineers develop more effective MRI contrast agent for cancer detection

PET Technique Promises Better Detection and Therapy Response Assessment for a Deadly Form of Non-Hodgkin’s Lymphoma

A single cell endoscope

Yale researchers develop a way to monitor engineered blood vessels as they grow in patients

Integrated 3-D imaging facilitates human face transplantation

Combined arterial imaging technology reveals both structural and metabolic details

Cornell Reaches Two Milestones toward a New Coherent X-ray Source

Test Combination Helps Predict Alzheimer's Disease Risk

>> More in: Biomedical Imaging

Bio-Energy and Clean Tech

UGA discovery may allow scientists to make fuel from CO2 in the atmosphere

Breakthrough for solar cell research

Climate change, biofuels mandate would cause corn price spikes

DOE researchers achieve important genetic breakthroughs to help develop cheaper biofuels

Solar power development in US Southwest could threaten wildlife

Solar power much cheaper to produce than most analysts realize, study finds

Carbon Mitigation Strategy Uses Wood for Buildings First, Bioenergy Second

A Fifth of Global Energy Could Come from Biomass Without Damaging Food Production

How BP Blew Its Chance to Spearhead a Solar Innovation

Marines test new energy-efficient weapon in the war on trash

>> More in: Bio-Energy & Clean Tech

Ag-Bio & Bio-Agriculture

Accelerating adoption of agricultural technology

BGI study results on resequencing 50 accessions of rice cast new light on molecular breeding

Farming crucial for threatened species in developing world

Climate-smart agriculture should be livelihood-smart too

Stronger corn? Take it off steroids, make it all female

Thanksgiving in Space May One Day Come With All the Trimmings

Good Genes Yield High-Quality Meat Products

Agricultural Pest Management Program Efficiency Challenged by Information Diffusion Barriers Among Farmers

Endangered Species: Should Cheap Phosphorus Be First on an Elemental 'Red List?'

Examining Rice Genes for Rice Blast Resistance

>> More in: Ag-Bio & Bio-Agriculture

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