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Microbiology
Polar growth at the bacterial scale reveals potential new targets for antibiotic therapy PDF Print E-mail
Tuesday, 17 January 2012 22:34

BLOOMINGTON, Ind. -- An international team of microbiologists led by Indiana University researchers has identified a new bacterial growth process -- one that occurs at a single end or pole of the cell instead of uniform, dispersed growth along the long axis of the cell -- that could have implications in the development of new antibacterial strategies.

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Purdue scientists reveal how bacteria build homes inside healthy cells PDF Print E-mail
Wednesday, 21 December 2011 06:59

WEST LAFAYETTE, Ind. - Bacteria are able to build camouflaged homes for themselves inside healthy cells - and cause disease - by manipulating a natural cellular process.

Purdue University biologists led a team that revealed how a pair of proteins from the bacteria Legionella pneumophila, which causes Legionnaires disease, alters a host protein in order to divert raw materials within the cell for use in building and disguising a large structure that houses the bacteria as it replicates.

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Timing is everything: Bacterial attachment mimics the just-in-time industrial delivery model PDF Print E-mail
Thursday, 01 December 2011 05:22

Understanding mechanism may aid in development of infection-fighting drug.

BLOOMINGTON, Ind. -- In the human world of manufacturing, many companies are now applying an on-demand, just-in-time strategy to conserve resources, reduce costs and promote production of goods precisely when and where they are most needed. A recent study from Indiana University Bloomington scientists reveals that bacteria have evolved a similar just-in-time strategy to constrain production of an extremely sticky cement to exactly the appropriate time and place, avoiding wasteful and problematic production of the material.

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Human Norovirus in Groundwater Remains Infective After Two Months PDF Print E-mail
Saturday, 22 October 2011 03:07

20111022grmb03Researchers from Emory University have discovered that norovirus in groundwater can remain infectious for at least 61 days. The research is published in the October Applied and Environmental Microbiology.

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Viruses Coaxed to Form Synthetics With Microstructures Akin to Those of Corneas, Teeth and Skin PDF Print E-mail
Saturday, 22 October 2011 02:48

20111022grmb01Using a simple, single-step process, engineers and scientists at the University of California at Berkeley recently developed a technique to direct benign, filamentous viruses called M13 phages to serve as structural building blocks for materials with a wide range of properties.

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Fighting Cancer With Oncolytic Viruses PDF Print E-mail
Thursday, 20 October 2011 01:17
Oncolytic virology uses live viruses to sense the genetic difference between a tumor and normal cell. Once the virus finds a tumor cell, it replicates inside that cell, kills it and then spreads to adjacent tumor cells to seed a therapeutic "chain reaction".
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Trudeau Institute Announces Its Latest Discovery In The Fight Against Tuberculosis PDF Print E-mail
Tuesday, 18 October 2011 19:29
20111019grmb04New research from the Trudeau Institute may help in the ongoing fight against tuberculosis. Dr. Andrea Cooper's lab has discovered a connection between the development of new lymphoid tissue within the lung and protection against the disease.
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Bacteria Associated With Stomach Ulcers Not Detected In Enlarged Adenoids In Children PDF Print E-mail
Tuesday, 18 October 2011 05:46

20111018grmb02Bacteria that cause stomach inflammation and ulcers were not detectable in tissue from inflamed and enlarged adenoids in children, according to a report in the October issue of Archives of Otolaryngology – Head & Neck Surgery, one of the JAMA/Archives journals.

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Blocking MRSA Toxin May Help Treat Superbug Infections PDF Print E-mail
Saturday, 15 October 2011 00:52
The October 13 issue of the Open Access journal PLoS Pathogens reveals that researchers have discovered a toxin called SElX, released by Methicillin-resistant Staphylococcus aureus (MRSA) which leads the body's immune system to go into overdrive and damage healthy cells.
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How Common Hospital Bacterium Transforms Into Superbug PDF Print E-mail
Saturday, 15 October 2011 00:39
The October 13 issue of the Open Access journal PLoS Pathogens published research that uncovered how a common hospital bacterium transforms into a deadly super-bug killing increasing numbers of hospital patients worldwide.
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Exploiting Trichoderma: From food security to biotechnology PDF Print E-mail
Wednesday, 21 December 2011 07:25

From improving food security to their use as biotechnology power horses, Trichoderma fungi are increasingly being exploited by industry. Current advances in the field are brought together and highlighted in a special issue of Microbiology published online on 27 December.

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Researchers reveal SBP8a configurations PDF Print E-mail
Wednesday, 07 December 2011 00:52

New discovery bonds to anthrax spores, not just anthrax bacteria

A new study has shown previously unseen details of an anthrax bacteriophage — a virus that infects anthrax bacteria — revealing for the first time how it infects its host, and providing an initial blueprint for how the phage might someday be modified into a tool for the detection and destruction of anthrax and other potential bioterror agents.

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West Nile Virus Transmission Linked to Land Use Patterns and 'Super-Spreaders' PDF Print E-mail
Saturday, 22 October 2011 03:14

20111022grmb04After its initial appearance in New York in 1999, West Nile virus spread across the United States in just a few years and is now well established throughout North and South America.

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New Evidence for the Oldest Oxygen-Breathing Life On Land PDF Print E-mail
Saturday, 22 October 2011 02:57

20111022grmb02New University of Alberta research shows the first evidence that the first oxygen-breathing bacteria occupied and thrived on land 100 million years earlier than previously thought.

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Research Could Lead to New Treatments for Inflammatory Bowel Disease (IBD) and Viral Infections PDF Print E-mail
Thursday, 20 October 2011 01:19

20111020grmb02The intestinal ecosystem is even more dynamic than previously thought, according to two studies by UT Southwestern Medical Center researchers published in the latest issue of Science.

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Antibody Treatment Protects Monkeys from Hendra Virus Disease PDF Print E-mail
Thursday, 20 October 2011 01:07

20111020grmb01A human antibody given to monkeys infected with the deadly Hendra virus completely protected them from disease, according to a study published by National Institutes of Health (NIH) scientists and their collaborators.

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Immune Peacekeepers Discovered PDF Print E-mail
Tuesday, 18 October 2011 19:27
20111019grmb03There are more bacteria living on our skin and in our gut than cells in our body. We need them. But until now no-one knew how the immune system could tell that these bacteria are harmless.
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Researchers Find Possible Link Between Bacterium And Colon Cancer PDF Print E-mail
Tuesday, 18 October 2011 05:42
20111018grmb01Scientists at Dana-Farber Cancer Institute and the Broad Institute have found strikingly high levels of a bacterium in colorectal cancers, a sign that it might contribute to the disease and potentially be a key to diagnosing, preventing, and treating it.
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Southampton Scientists Herald Significant Breakthrough In Study Of Chlamydia PDF Print E-mail
Saturday, 15 October 2011 00:42

20111015grmb02A breakthrough in the study of chlamydia genetics could open the way to new treatments and the development of a vaccine for this sexually transmitted disease.

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Cholesterol Lowering By Statins May Be Affected By Gut Bacteria PDF Print E-mail
Saturday, 15 October 2011 00:27
20111015grmb01Statins can be effective at lowering cholesterol, but they have a perplexing tendency to work for some people and not others. Gut bacteria may be the reason.
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