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Molecular Mechanism Underlying Form Of Diabetes Revealed PDF Print E-mail
Saturday, 12 September 2009 11:17

By investigating a rare and severe form of diabetes in children, University of Iowa researchers have discovered a new molecular mechanism that regulates specialized pancreatic cells and insulin secretion. The mechanism involves a protein called ankyrin, which UI researchers previously linked to potentially fatal human heart arrhythmias. The findings, which appear this week in the Early Edition of the Proceedings of the National Academy of Sciences, may help identify new molecular targets for treating both rare and common forms of diabetes and hyperinsulinemia.

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Insomnia Is Bad For The Heart; Increases Blood Pressure PDF Print E-mail
Saturday, 12 September 2009 11:06

Can't sleep at night? A new study published in the journal Sleep has found that people who suffer from insomnia have heightened nighttime blood pressure, which can lead to cardiac problems. The investigation, which measured the 24-hour blood pressure of insomniacs compared to sound sleepers, was conducted by researchers from the Université de Montréal, its affiliated Hôpital du Sacré-Cœur de Montréal Sleep Disorders Centre and the Université Laval.

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US Swine Flu Death Toll Includes 36 Children, Report PDF Print E-mail
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Friday, 04 September 2009 04:58

Federal officials reported this week that at least 36 children have died in the US as result of the 2009 pandemic swine flu virus A(H1N1), two thirds of whom had one or more high risk medical conditions. Over 90 per cent of the children who had medical conditions had neurodevelopmental disorders such as developmental delay or cerebral palsy and health-care professionals are urged to be aware of the potential for more severe illness, including death, among these children. The report also shows that most of the children with neurodevelopmental conditions who died had more than one neurodevelopmental diagnosis and/or pulmonary conditions.

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Cardiac Surgeons Implant World's First New DeBakey Heart Assist Device PDF Print E-mail
Tuesday, 01 September 2009 23:57

At the end of July 2009, a team of cardiac surgeons headed by Professor Dr. Matthias Karck, Director of the Department of Cardiac Surgery at Heidelberg University Hospital, was the first in the world to implant the HeartAssist 5 ventricular assist device, the modern version of the DeBakey VAD. The device augments the pumping function of the left ventricle in an especially effective, gentle and quiet manner. The pump weighs 92 grams and is made of titanium and plastic. It pumps blood from the weakened or failed left ventricle into the aorta.

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New Hope For Heart Failure Patients: Cardiac Resynchronization PDF Print E-mail
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Tuesday, 01 September 2009 23:50

Patients who had a cardiac resynchronization device combined with a defibrillator (CRT-D) implanted had a 34 percent reduction in their risk of death or heart failure when compared to patients receiving only an implanted cardiac defibrillator (ICD), according to a landmark study published online in the New England Journal of Medicine and presented today at the European Society of Cardiology Congress (ESC) in Barcelona, Spain.

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Valsartan Reduces Morbidity And Mortality In Japanese Patients With High Risk Hypertension: Results From The KYOTO HEART Study PDF Print E-mail
Tuesday, 01 September 2009 23:19

The KYOTO HEART Study, which took place in Japan between January 2004 and January 2009, shows that the addition of valsartan to conventional antihypertensive treatment to improve blood pressure control is associated with an improved cardiovascular outcome in Japanese hypertensive patients at high risk of CVD events.

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Psychosocial Therapy With Antidepressants More Effective In Helping Depressed Stroke Patients PDF Print E-mail
Monday, 31 August 2009 03:33

Psychosocial therapy combined with medication can effectively improve depression and recovery in stroke patients, according to a new study reported in Stroke: Journal of the American Heart Association. In the first long-term study of psychosocial/behavioral therapy in combination with antidepressants, researchers found that adding psychosocial therapy improved depression scores short term and those improvements were sustained long term.

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Abnormal Heartbeats Caused By Changes In Ion Channel Density PDF Print E-mail
Monday, 31 August 2009 03:24

Two independent studies have determined how changes in the density of different ion channels in the surface membrane of heart muscle cells can lead to life-threatening abnormal heartbeats, according to research to be published in the August 24 issue of the Journal of Clinical Investigation. As Gail Robertson, at the University of Wisconsin — Madison, discusses in an accompanying commentary, these important studies provide new insight into the complex array of mechanisms controlling our heartbeat and how they can be perturbed.

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High Blood Pressure Linked To Memory Problems In Middle Age PDF Print E-mail
Friday, 28 August 2009 03:30

High blood pressure is linked to memory problems in people over 45, according to research published in the August 25, 2009, print issue of Neurology®, the medical journal of the American Academy of Neurology. The study found that people with high diastolic blood pressure, which is the bottom number of a blood pressure reading, were more likely to have cognitive impairment, or problems with their memory and thinking skills, than people with normal diastolic readings.

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Cardiac Arrest Casualties Form Valuable Source Of Donor Kidneys PDF Print E-mail
Friday, 28 August 2009 03:24

A pilot study of a system for harvesting kidneys from non-heart-beating donors where attempts of resuscitation after a witnessed out-of-hospital cardiac arrest have failed (uncontrolled NHBDs) resulted in 21 successful kidney transplants - a 10% increase in the transplantation rate - over 17 months. Researchers have shown that retrieval from uncontrolled NHBDs may provide a valuable source of organs and could help counter the shortage of kidney grafts in France.

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Link Found Between Depression, Early Stages Of Chronic Kidney Disease PDF Print E-mail
Saturday, 12 September 2009 11:10

One in five patients with chronic kidney disease is depressed, even before beginning long-term dialysis therapy or developing end-stage renal disease, UT Southwestern Medical Center researchers have found. The study, based on a pool of 272 participants, is the first to examine the rate of depression among these patients using the Diagnostic and Statistical Manual of Mental Disorders 4th edition (DSM IV), which is considered the gold-standard in evaluating depression.

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Debate On "Low Carbohydrate High Fat Diet" Trends In Sweden PDF Print E-mail
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Friday, 04 September 2009 05:01
A comment published in this week's edition of The Lancet reports that nutrition experts have expressed their astonishment over the involvement of Sweden in a debate concerning support of low carbohydrate high fat (LCHF) diets in the country. The comment is the work of Dr Jim Mann and Dr Edwin R Nye, University of Otago, Dunedin, New Zealand.
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Individuals With Large Thighs Have A Lower Risk Of Heart Disease And Early Death PDF Print E-mail
Friday, 04 September 2009 04:50
Research just published on bmj.com reports that men and women whose thighs are less than 60cm in circumference have a higher risk of premature death and heart disease. The study also concluded that individuals whose thighs are wider than 60cm have no additional protective effect. Professor Berit Heitmann is the lead author and based at Copenhagen University Hospital. He explains that his research may help GPs identify patients who are at an increased risk of early death and developing heart disease.
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Regular Electrocardiograms May Help Physicians Identify Patients At Risk Of Sudden Cardiac Death PDF Print E-mail
Tuesday, 01 September 2009 23:53

QRS duration (QRSd) is one of several measures of heart function recorded during a routine electrocardiogram (ECG). It is a composite of waves showing the length of time it takes for an electrical signal to get all the way through the pumping chambers of the heart. Prolonged QRSd is a sign of an abnormal electrical system of the heart and is often found when the heart isn't pumping efficiently.

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Inflammatory Diseases Linked To Increased Cardiovascular Risk PDF Print E-mail
Tuesday, 01 September 2009 23:23

Patients suffering from two serious autoimmune disorders which cause muscular inflammation are at increased risk of developing cardiovascular disease, says a group of Montreal researchers. Dr. Christian A. Pineau and his team at the Research Institute of the McGill University Health Centre (RI-MUHC) have linked muscular inflammation to increased cardiovascular risk for the first time. Their results were published recently in The Journal of Rheumatology.

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New Information About How Fat Increases Blood Pressure Could Help Identify Those At Risk PDF Print E-mail
Tuesday, 01 September 2009 23:16

Some of the first information about how fat causes hypertension have been identified by researchers who say the findings should one day help identify which obese people – and maybe some thin ones too – are at risk for hypertension and which drugs would work best for them. Medical College of Georgia researchers have found that deleting or mutating the gene PTP1B puts mice at risk for hypertension by interfering with an endogenous mechanism that should help prevent it. The findings are published in the Sept. 1 issue of the American Heart Association journal Circulation.

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Blood Thinner Causes Stroke In Some Dialysis Patients, Study Suggests PDF Print E-mail
Monday, 31 August 2009 03:29

The blood thinner warfarin can prevent strokes in most individuals with abnormal heart rhythms, but the drug may have the opposite effect in kidney disease patients on dialysis, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The results suggest that warfarin should be prescribed with caution in patients with kidney failure.

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Protein Involved In Causing Gum Disease, Osteoporosis, Arthritis Identified PDF Print E-mail
Monday, 31 August 2009 03:17

Investigators at Hospital for Special Surgery, collaborating with researchers from other institutions, have contributed to the discovery that a gene called interferon regulator factor-8 (IRF-8) is involved in the development of diseases such as periodontitis (gum disease), rheumatoid arthritis and osteoporosis. The study, which will be published online August 30, ahead of print, in the journal Nature Medicine, could lead to new treatments in the future.

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Beta-blockers And Stroke: New Insights Into Their Use For Older People PDF Print E-mail
Friday, 28 August 2009 03:27

A University of Leicester-led study may have uncovered the reason why Beta-blockers are less effective at preventing stroke in older people with high blood pressure, when compared to other drugs for high blood pressure. The research, carried out by Bryan Williams, Professor of Medicine at the University of Leicester, and his colleague Dr. Peter Lacy, has been published in the Journal of the American College of Cardiology and has been cited on the MDLinx.com site as currently the world’s number one leading finding in its field.

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Working Too Much Can Be Dangerous For Teen's Sexual Health, Study Shows PDF Print E-mail
Friday, 28 August 2009 03:19

Allowing teens to work too many hours in the wrong environment can be dangerous for their sexual health by fostering conditions that lead them to older sex partners, a new study shows. This is just one of the key findings in a University of Michigan study of youth on what predicts age of sex partners. Jose Bauermeister, one of the authors, says age difference of sex partners is important, because a larger age difference is associated with riskier sexual behavior and STDs, including HIV.

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