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Drug doesn't significantly lower risk of major heart problems in dialysis patients PDF Print E-mail
Monday, 05 November 2012 07:09

In one of the largest and longest trials involving patients with kidney failure, a study led by an international team of researchers found that cinacalcet — a drug commonly prescribed to patients with kidney failure and a disturbance of bone and mineral metabolism known as secondary hyperparathyroidism — does not significantly reduce the risk of death or major cardiovascular events.

Immune system fighters speak in patterns of proteins, prefer squishy partners PDF Print E-mail
Friday, 26 October 2012 22:22

When talking to the key immune system fighters known as T-cells, it helps to speak their language. Now researchers from Columbia University in New York, N.Y., and the University of Pennsylvania in Philadelphia have discovered two new conditions for communication that may help scientists one day harness the power of T-cells to fight diseases such as cancer. The team will present its findings at the AVS 59th International Symposium and Exhibition, held Oct. 28 – Nov. 2 in Tampa, Fla.

Patient navigation leads to faster diagnosis for breast cancer, according to new study PDF Print E-mail
Sunday, 07 October 2012 21:21

WASHINGTON, D.C. –Today researchers from The George Washington University published a study showing that breast cancer patients can reduce potentially dangerous delays in the identification of breast cancer with the assistance of patient navigation services. Patient navigation—a service that helps patients overcome barriers to getting health care, including setting up appointments, dealing with health insurance, and helping with fears about cancer—led to a nearly four-fold reduction in the time it took to diagnose a suspicious breast lump, the new study found.

Manipulating the microbiome could help manage weight PDF Print E-mail
Monday, 27 August 2012 00:37

Vaccines and antibiotics may someday join caloric restriction or bariatric surgery as a way to regulate weight gain, according to a new study focused on the interactions between diet, the bacteria that live in the bowel, and the immune system.

Anti-clotting drugs yield similar results PDF Print E-mail
Monday, 27 August 2012 00:30

Potential long-term benefit observed for first time in ACS patients

DURHAM, N.C.— The first trial to study patients with acute coronary syndrome who do not undergo coronary stenting or bypass surgery found no significant difference between two anti-clotting drugs – prasugrel and clopidogrel – in preventing the first occurrence of death, heart attack or stroke, according to Duke University Medical Center cardiologists.

UCLA researchers discover that fluoxetine -- a.k.a., Prozac -- is effective as an anti-viral PDF Print E-mail
Sunday, 29 July 2012 21:47

UCLA researchers have come across an unexpected potential use for fluoxetine – commonly known as Prozac – which shows promise as an antiviral agent. The discovery could provide another tool in treating human enteroviruses that sicken and kill people in the U.S. and around the world.

An economical, effective and biocompatible gene therapy strategy promotes cardiac repair PDF Print E-mail
Sunday, 08 July 2012 20:16

Dr Changfa Guo, Professor Chunsheng Wang and their co-investigators from Zhongshan hospital Fudan University, Shanghai, China have established a novel hyperbranched poly(amidoamine) (hPAMAM) nanoparticle based hypoxia regulated vascular endothelial growth factor (HRE-VEGF) gene therapy strategy which is an excellent substitute for the current expensive and uncontrollable VEGF gene delivery system. This discovery, reported in the June 2012 issue of Experimental Biology and Medicine, provides an economical, feasible and biocompatible gene therapy strategy for cardiac repair.

JDRF-funded research shows some may be protected from diabetic eye disease PDF Print E-mail
Monday, 11 June 2012 15:12

Researchers at Joslin Diabetes Center hope to use experiences of people with long-term type 1 diabetes to benefit others

New York, NY, June 11, 2012—Researchers at Joslin Diabetes Center, supported by JDRF, have completed a study of 158 people who have lived with type 1 diabetes (T1D) for 50 years or more with eye examinations at Joslin over many decades of follow-up, and have concluded that a high proportion of this unique group of patients developed little to no diabetic eye disease over time. The study focuses on a group of patients known as "50-year Medalists," and was funded by JDRF in support of its efforts to improve the lives of people with T1D by reducing or eliminating the impact of its complications. Their results, which researchers hope will lead to a means to prevent or slow the progression of the disease, were presented at the 72nd American Diabetes Association's (ADA) Scientific Sessions in Philadelphia this past weekend.

High-fat diet lowered blood sugar and improved blood lipids in diabetics PDF Print E-mail
Sunday, 13 May 2012 05:35

People with Type 2 diabetes are usually advised to keep a low-fat diet. Now, a study at Linköping University shows that food with a lot of fat and few carbohydrates could have a better effect on blood sugar levels and blood lipids.

Gene involved in sperm-to-egg binding is key to fertility in mammals PDF Print E-mail
Tuesday, 01 May 2012 00:58

Experts from Durham University have identified a new gene that could help the development of fertility treatments in humans in the future.

Scientists from Durham University, UK, and Osaka University, Japan, looking at fertility in mice, have discovered for the first time that the gene, which makes a protein called PDILT, enables sperm to bind to an egg, a process essential to fertilisation.

Mayo Clinic identifies promising treatment for inherited form of kidney disease PDF Print E-mail
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Monday, 05 November 2012 07:08

SAN DIEGO -- A drug therapy shows promise for treating an inherited form of kidney disease called autosomal dominant polycystic kidney disease (ADPKD), Mayo Clinic researchers say. The medication, tolvaptan, slowed the pace of kidney cyst growth over the three years of the study. The phase three clinical trial results were being presented today at the American Society of Nephrology annual meeting and published online in theNew England Journal of Medicine.

A Viagra follow-up? Drug used to treat glaucoma actually grows human hair PDF Print E-mail
Friday, 26 October 2012 21:26

New research in the FASEB Journal shows how a commonly prescribed glaucoma drug may be effective in treating male pattern baldness and other forms of alopecia

Diet high in total antioxidants associated with lower risk of myocardial infarction in women PDF Print E-mail
Sunday, 23 September 2012 03:10

New findings reported in the American Journal of Medicine

Philadelphia, PA, September 21, 2012 – Coronary heart disease is a major cause of death in women. A new study has found that a diet rich in antioxidants, mainly from fruits and vegetables, can significantly reduce the risk of myocardial infarction. The study is published in the October issue of The American Journal of Medicine.

New device to remove stroke-causing blood clots proves better than standard tool PDF Print E-mail
Monday, 27 August 2012 00:33

Stroke is the fourth leading cause of death and a common cause of long-term disability in the United States, but doctors have very few proven treatment methods. Now a new device that mechanically removes stroke-causing clots from the brain is being hailed as a game-changer.

Cell receptor has proclivity for T helper 9 cells, airway inflammation PDF Print E-mail
Sunday, 29 July 2012 21:59

Findings may affect how doctors treat allergic inflammation and organ transplant rejection

BOSTON, MA—A research team led by Xian Chang Li, MD, PhD, Brigham and Women's Hospital (BWH) Transplantation Research Center, has shed light on how a population of lymphocytes, called CD4+ T cells, mature into various subsets of adult T helper cells. In particular, the team uncovered that a particular cell surface molecule, known as OX40, is a powerful inducer of new T helper cells that make copious amounts of interleukin-9 (IL-9) (and therefore called TH9 cells) in vitro; such TH9 cells are responsible for ongoing inflammation in the airways in the lungs in vivo.

What happens when we sunburn PDF Print E-mail
Sunday, 08 July 2012 22:36

Researchers describe inflammatory mechanism for first time.

The biological mechanism of sunburn – the reddish, painful, protective immune response from ultraviolet (UV) radiation – is a consequence of RNA damage to skin cells, report researchers at the University of California, San Diego School of Medicine and elsewhere in the July 8, 2012 Advance Online Publication of Nature Medicine.

U of M researchers find natural antioxidant can protect against cardiovascular disease PDF Print E-mail
Sunday, 17 June 2012 19:26

MINNEAPOLIS/ST. PAUL (06/15/2012) – University of Minnesota Medical School researchers have collaborated with the School of Public Health and discovered an enzyme that, when found at high levels and alongside low levels of HDL (good cholesterol), can dramatically reduce the risk of cardiovascular disease.

First study to suggest that the immune system may protect against Alzheimer's changes in humans PDF Print E-mail
Sunday, 27 May 2012 05:55

Recent work in mice suggested that the immune system is involved in removing beta-amyloid, the main Alzheimer's-causing substance in the brain. Researchers have now shown for the first time that this may apply in humans.

A New Drug to Manage Resistant Chronic Pain PDF Print E-mail
Tuesday, 01 May 2012 01:01 develops "BL-7050" to ease the neuropathic pain of millions of sufferers.

Neuropathic pain, caused by nerve or tissue damage, is the culprit behind many cases of chronic pain. It can be the result of an accident or caused by a variety of medical conditions and diseases such as tumors, lupus, and diabetes. Typically resistant to common types of pain management including ibuprofen and even morphine, neuropathic pain can lead to lifelong disability for many sufferers.

2 drugs better than 1 to treat youth with type 2 diabetes PDF Print E-mail
Monday, 30 April 2012 03:46

NIH-funded study addresses emerging health problem

A combination of two diabetes drugs, metformin and rosiglitazone, was more effective in treating youth with recent-onset type 2 diabetes than metformin alone, a study funded by the National Institutes of Health (NIH) has found. Adding an intensive lifestyle intervention to metformin provided no more benefit than metformin therapy alone.

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