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Thursday, 30 July 2009 04:29 |
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Researchers at Dana-Farber Cancer Institute have shown that they can engineer mouse and human cells to produce brown fat, a natural energy-burning type of fat that counteracts obesity. If such a strategy can be developed for use in people, the scientists say, it could open a novel approach to treating obesity and diabetes.
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Thursday, 30 July 2009 03:11 |
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An international team of scientists and clinicians from the United States and Saudi Arabia are working to develop gene therapy for treating a rare, hereditary retinal disease. The therapy has been shown to restore lost vision in animal models of retinitis pigmentosa (RP). Their work is being funded in part by a $1.5 million grant from the Prince Salman Center for Disability Research in Saudi Arabia, where the recessive gene mutation that leads to the eye disease RP has been found in children from several families. |
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Tuesday, 28 July 2009 03:25 |
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Researchers at Rice University and their international colleagues have for the first time described the atomic structure of the protein shell that carries the genetic code of hepatitis E (HEV). Their finding could mean that new ways to stop the virus may come in the not-too-distant future.
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Tuesday, 28 July 2009 02:44 |
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Computer scientists and biologists at the University of Southampton have used the combined power of computing resources within the institution to develop software which provides a better understanding of how viruses evolve. |
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Monday, 27 July 2009 04:07 |
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Scientists are closer to understanding how to grow replacement bones with stem cell technology, thanks to research published today in the journal Nature Materials. |
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Friday, 24 July 2009 07:50 |
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Scientists from The Medical College of Wisconsin in Milwaukee, Sangamo Biosciences, Inc., Sigma-Aldrich Corporation, Open Monoclonal Technology, Inc. and INSERM have announced the creation of the first genetically modified mammals developed using zinc finger nuclease (ZFN) technology. |
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Thursday, 23 July 2009 06:22 |
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Johns Hopkins researchers have developed a novel way to monitor in real time the behavior of the TB bacterium in mouse lungs noninvasively pinpointing the exact location of Mycobacterium tuberculosis. The new monitoring system is expected to speed up what is currently a slow and cumbersome process to test the safety and efficacy of various TB drug regimens and vaccines in animals. Plans are already under way for developing a similar system to monitor TB disease in humans.
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Tuesday, 21 July 2009 03:38 |
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Arctic springtails (Megaphorura arctica) survive freezing temperatures by dehydrating themselves before the coldest weather sets in. Researchers have now identified a suite of genes involved in controlling this extreme survival mechanism.
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Tuesday, 21 July 2009 03:34 |
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Using a combination of sensory, genetic, and in vitro approaches, researchers from the Monell Center confirm that the T1R1-T1R3 taste receptor plays a role in human umami (amino acid) taste.
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Tuesday, 14 July 2009 09:24 |
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An iconic photograph of Nobel laureates Drs. Francis Crick and James Watson show the pair discussing with a rigid model of the famous double helix. |
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Thursday, 30 July 2009 04:27 |
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Italian and U.S. biologists have report that a little-understood protein previously implicated in a rare genetic disorder plays an unexpected and critical role in building and maintaining healthy cells. Even more surprising, their report in the journal Nature shows that the protein, called "atlastin," does its work by fusing intracellular membranes in a previously undocumented way.
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Tuesday, 28 July 2009 11:28 |
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Scientists at the University of Bristol in the UK and the Max Planck in Germany have developed the world’s first “liquid protein” that could have a big impact on the delivery of therapeutic proteins and high-potency pharmaceuticals. |
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Tuesday, 28 July 2009 03:22 |
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Nearly all species have some ability to detect light. At least three types of cells in the retina allow us to see images or distinguish between night and day. Now, researchers at the Johns Hopkins School of Medicine have discovered in fish yet another type of cell that can sense light and contribute to vision.
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Tuesday, 28 July 2009 02:40 |
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Two University of British Columbia researchers are part of an international team recommending standards for the DNA barcoding of land plants, a step they hope will lead to a universal system for identifying over 400,000 species, and ultimately boost conservation efforts. |
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Friday, 24 July 2009 20:55 |
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The "sloppier copier" discovered by USC biologists is also the best sixth man in the DNA repair game, an article in the journal Nature shows. |
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Friday, 24 July 2009 01:19 |
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Researchers at the University of Warwick have recovered significant DNA information from a lost form of ancient barley that triumphed for over 3000 years seeing off: 5 changes in civilisation, water shortages and a much more popular form of barley that produces more grains. This discovery offers a real insight into the couture of ancient farming and could assist the development of new varieties of crops to face today's climate change challenges.
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Tuesday, 21 July 2009 03:40 |
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More and more bacterial stems are developing resistance to previously life-saving antibiotics. Physicians have been warning that fatality rates from infections could increase dramatically in the very near future. Researchers at the Technische Universität München (TUM) have now cast light on a metabolic step that appears in many aggressive microorganisms like tuberculosis or malaria pathogens and that may provide a promising target for a new class of antibiotics.
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Tuesday, 21 July 2009 03:37 |
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Infections of wounds, pneumonia, etc. in hospitals in particular are often caused by bacteria called Pseudomonas aeruginosa. Once they reach a certain density, colonies of Pseudomonas aeruginosa produce virulence factors and can enter into a slimy state, a biofilm, which prevents antibiotics from penetrating. The process of quorum sensing, which cells use to “sense” cell density, is triggered when the concentration of certain signaling compounds generated by the bacteria reaches a threshold level.
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Tuesday, 14 July 2009 09:25 |
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Researchers funded by the National Institutes of Health have completed a critical first step in the eventual development of a technique to retain fertility in women with cancer who require treatments that might otherwise make them unable to have children.
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Tuesday, 14 July 2009 09:23 |
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They’ve been dubbed “grassoline” - second generation biofuels made from inedible plant material, including fast-growing weeds, agricultural waste, sawdust, etc. - and numerous scientific studies have shown them to be prime candidates for replacing gasoline to meet our transportation needs. However, before we can begin to roll down the highways on sustainable, carbon-neutral grassoline, numerous barriers must be overcome, starting with finding ways to break lignocellulosic biomass down into fermentable sugars.
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