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Biotechnology
Development of More Muscular Trout Could Boost Commercial Aquaculture PDF Print E-mail
Thursday, 11 March 2010 08:55

A 10-year effort by a University of Rhode Island scientist to develop transgenic rainbow trout with enhanced muscle growth has yielded fish with what have been described as six-pack abs and muscular shoulders that could provide a boost to the commercial aquaculture industry.

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Asexual Plant Reproduction May Seed New Approach for Agriculture PDF Print E-mail
Thursday, 11 March 2010 08:50

Farmers throughout the world spend an estimated $36 billion a year to buy seeds for crops, especially those with sought after traits such as hardiness and pest-resistance. They can't grow these seeds themselves because the very act of sexual reproduction erases many of those carefully selected traits. So year after year, farmers must purchase new supplies of specially-produced seeds.

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New Technique Allows Study of Protein Folding, Dynamics in Living Cells PDF Print E-mail
Monday, 08 March 2010 08:42

A new technique to study protein dynamics in living cells has been created by a team of University of Illinois scientists, and evidence yielded from the new method indicates that an in vivo environment strongly modulates a protein's stability and folding rate, according to research accepted for publication in the journal Nature Methods and posted on the journal's Web site Feb. 28.

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Predicting the Fate of Stem Cells: New Method Decodes Cell Movements, Accurately Predicts How Cells Will Divide PDF Print E-mail
Monday, 08 March 2010 08:37

Researchers at Rensselaer Polytechnic Institute have discovered a new method for predicting -- with up to 99 percent accuracy -- the fate of stem cells. Using advanced computer vision technology to detect subtle cell movements that are impossible to discern with the human eye, Professor Badri Roysam and his former student Andrew Cohen '89 can successfully forecast how a stem cell will split and what key characteristics the daughter cells will exhibit.

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Biologists Use Mathematics to Advance Our Understanding of Health and Disease PDF Print E-mail
Tuesday, 02 March 2010 00:02

Math-based computer models are a powerful tool for discovering the details of complex living systems. John Tyson, professor of biology at Virginia Tech, is creating such models to discover how cells process information and make decisions.

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Gene-Based Stem Cell Therapy Specifically Removes Cell Receptor That Attracts HIV PDF Print E-mail
Monday, 01 March 2010 23:59

UCLA AIDS Institute researchers successfully removed CCR5 -- a cell receptor to which HIV-1 binds for infection but which the human body does not need -- from human cells. Individuals who naturally lack the CCR5 receptor have been found to be essentially resistant to HIV.

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Stem Cells Restore Sight in Mouse Model of Retinitis Pigmentosa PDF Print E-mail
Friday, 26 February 2010 22:47

An international research team led by Columbia University Medical Center successfully used mouse embryonic stem cells to replace diseased retinal cells and restore sight in a mouse model of retinitis pigmentosa. This strategy could potentially become a new treatment for retinitis pigmentosa, a leading cause of blindness that affects approximately one in 3,000 to 4,000 people, or 1.5 million people worldwide.

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Diffusion of a Soluble Protein Through a Sensory Cilium PDF Print E-mail
Friday, 26 February 2010 22:45

A team of researchers led by Peter Calvert (SUNY Upstate Medical University) has, for the first time, measured the diffusion coefficient of a protein in a primary cilium and in other major compartments of a highly polarized cell. The study appears in the March issue of the Journal of General Physiology.

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New Method Makes Vaccines Stable at Tropical Temperatures PDF Print E-mail
Sunday, 21 February 2010 00:19

A simple and cheap way of making vaccines stable -- even at tropical temperatures -- has been developed by scientists at Oxford University and Nova Bio-Pharma Technologies.

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Scientists Transplant Nose of Mosquito, Advance Fight Against Malaria PDF Print E-mail
Thursday, 18 February 2010 09:18

Scientists at Vanderbilt and Yale universities have successfully transplanted most of the "nose" of the mosquito that spreads malaria into frog eggs and fruit flies and are employing these surrogates to combat the spread of the deadly and debilitating disease that afflicts 500 million people. The research is described in two complimentary papers, one published this week in the early online edition of the Proceedings of the National Academy of Sciences and the other which appeared online Feb. 3 in the journal Nature.

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Genetically Engineered Tobacco Plant Cleans Up Environmental Toxin PDF Print E-mail
Thursday, 11 March 2010 08:54

Tobacco might become as well known for keeping us healthy as it is for causing illness thanks to researchers from the U.K. In a new research report appearing in the March 2010 print issue of the FASEB Journal, scientists explain how they developed a genetically modified strain of tobacco that helps temper the damaging effects of toxic pond scum, scientifically known as microcystin-LR (MC-LR), which makes water unsafe for drinking, swimming, or fishing. This plant could serve as a major tool for helping keep water sources safe to use, especially in developing nations.

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Reovirus May Be a Novel Approach to Prostate Cancer Treatment PDF Print E-mail
Thursday, 11 March 2010 08:45

Researchers in Canada have detected a novel oncolytic viral therapy against prostate cancer with use of a virus called the reovirus, according to study results published in Cancer Research, a journal of the American Association for Cancer Research.

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Mosses, Deep-Frozen PDF Print E-mail
Monday, 08 March 2010 08:40

In the life sciences, the safe long-term storage of living materials such as cells or whole organisms, as well as their worldwide exchange between research groups, is becoming more and more important. The University of Freiburg now supports this free material transfer with the establishment of an international centre for research with mosses.

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New Basis for Drug Development: Structure Determination of Biomolecules in Their Natural Environment PDF Print E-mail
Monday, 08 March 2010 08:33

Scientists from the Helmholtz Zentrum München and the Technische Universität München (TUM) under the direction of Prof. Michael Sattler have developed a new strategy allowing them to determine the spatial structure of biomolecules in solution. The method is flexible and generally applicable to obtaining structural information for signal forwarding pathways in the cell or in the regulation of gene expression.

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Novel Antitoxin Strategy Developed Using 'Tagged Binding Agents' PDF Print E-mail
Tuesday, 02 March 2010 00:00

A study involving the world's deadliest substance has yielded a new strategy to clear toxins from the body -- which may lead to more efficient strategies against toxins that may be used in a bioterrorist event, as well as snake bites, scorpion stings, and even some important chronic diseases.

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Nanotechnology Tackles the Two Biggest Problems Associated With Chemotherapy PDF Print E-mail
Monday, 01 March 2010 23:58

Huixin He, associate professor of nanoscale chemistry at Rutgers University, Newark, and Tamara Minko, professor at the Rutgers Ernest Mario School of Pharmacy, have developed a nanotechnology approach that potentially could eliminate the problems of side effects and drug resistance in the treatment of cancer. Under traditional chemotherapy, cancer cells, like bacteria, can develop resistance to drug therapy, leading to a relapse of the disease.

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The Pig and Its Pancreas: A Unique Model for a Common Disease PDF Print E-mail
Friday, 26 February 2010 22:46

The increasing prevalence of type 2 diabetes places a huge burden on its victims and poses a tremendous challenge to healthcare systems. Half of all heart attacks and stroke cases, but also many other deleterious conditions, can be ascribed to the effects of this metabolic syndrome. In Germany alone, some seven million people currently suffer from the disease, and the number of cases worldwide is projected to reach 370 million by the year 2030.

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Mouse Model May Provide Insight Into the Schizophrenic Brain PDF Print E-mail
Friday, 26 February 2010 20:47

Schizophrenia is an incredibly complex and profoundly debilitating disorder that typically manifests in early adulthood but is thought to arise, at least in part, from pathological disturbances occurring during very early brain development. Now, a new study published by Cell Press in the February 25 issue of the journal Neuron, manipulates a known schizophrenia susceptibility gene in the brains of fetal mice to begin to unravel the complex link between prenatal brain development and maturation of information processing and cognition in adult animals.

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Critical Step in Fly Vision Discovered; Offers Clues to Treating Retinal Degeneration in Humans PDF Print E-mail
Thursday, 18 February 2010 09:24

Research by Johns Hopkins sensory biologists studying fruit flies has revealed a critical step in fly vision. Humans with problems in this same step suffer retinal dystrophies, which manifest as visual defects ranging from mild visual impairments to complete blindness. The article, published Jan. 26 in Current Biology, paves the way for using the fruit fly to screen for therapies to treat human retinal degeneration.

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Engineer Creates Unique Software That Predicts Stem Cell Fate PDF Print E-mail
Thursday, 18 February 2010 09:07

A software program created by an engineer at the University of Wisconsin-Milwaukee (UWM) can not only predict the types of specialized cells a stem cell will produce, but also foresee the outcome before the stem cell even divides.

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