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Thursday, 20 October 2011 03:17 |
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Joan Steitz has been a leader in the field of RNA biology for a generation, from her graduate work on the structure and function of RNA in RNA-containing bacterial viruses (bacteriophages), to the discovery of the role of small nuclear and nucleolar ribonucleoprotein particles (snRNPs and snoRNPs) in RNA processing, and the discovery of a rare mRNA processing pathway.
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Thursday, 06 October 2011 03:04 |
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Prof Alan Hall has been a pioneer in showing how external signals control the cellular cytoskeleton, composed of proteins such as actin, which in turn organizes the shape and movement of cells. His research revealed a series of crucial molecular switches (called Rho GTPases), which acting together determine when and where the cell's outer membrane and actin cytoskeleton become rearranged to drive changes in cell migration. These are crucial features of cellular function in normal tissues, and critical for the aberrant behaviour of cancer cells. Dr. Hall's work has therefore transformed our understanding of the biology of human cells.
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Thursday, 22 September 2011 02:19 |
Proper chromosome segregation during mitosis is essential for all life, and has been one of the outstanding problems in cell biology for over 100 years. Nasmyth has dominated the field of mitotic regulation with a series of incisive discoveries, including characterization of the anaphase promoting complex that degrades mitotic cyclins, the cohesin complex that links sister chromatids together prior to mitosis, and most importantly, the novel proteolytic mechanism that rapidly breaks up sister chromatid cohesion at the onset of mitosis. Nasmyth's work on fundamental aspects of cell divison has profound implications for our understanding of chromosome non-disjunction in human cancer and other genetic diseases.
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Thursday, 01 September 2011 22:21 |
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Lucy Shapiro is a Professor in the Department of Developmental Biology at Stanford University School of Medicine where she holds the Virginia and D. K. Ludwig Chair in Cancer Research and is the Director of the Beckman Center for Molecular and Genetic Medicine. She received her Ph.D. in Molecular Biology from Albert Einstein College of Medicine. She joined the faculty of Stanford University School of Medicine in 1989 and served as the founding Chair of the Department of Developmental Biology from 1989-1997. Prior to coming to Stanford, Professor Shapiro was the Higgins Professor and Chair of Microbiology at the College of Physicians and Surgeons of Columbia University, and prior to that she held the Lola and Saul Kramer Endowed Chair at Albert Einstein College of Medicine where she was Chair of the Department of Molecular Biology.
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Wednesday, 17 August 2011 23:36 |
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A native of Rhode Island, Dr. William A. Catterall received his B.A. degree in Chemistry from Brown University in 1968, his Ph.D. in Physiological Chemistry from Johns Hopkins School of Medicine in 1972, and his postdoctoral training in neurobiology and molecular pharmacology as a Muscular Dystrophy Association Research Fellow with Dr. Marshall Nirenberg at the National Institutes of Health from 1972 to 1974. Following three more years as a staff scientist at the National Institutes of Health, he joined the faculty of the University of Washington School of Medicine in 1977 as an associate professor in the Department of Pharmacology, became professor in 1981, and Chair of the Department of Pharmacology in 1984.
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Wednesday, 03 August 2011 23:27 |
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Peter J. Ratcliffe was educated at Lancaster Royal Grammar winning an open scholarship to Gonville and Caius College, Cambridge in 1972. He studied Medicine at Cambridge and St Bartholomew's Hospital, London graduating with Distinction in 1978. He trained in renal medicine at Oxford initially working on the physiology of renal oxygenation and its implications for renal injury in shock.
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Tuesday, 19 July 2011 18:58 |
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Dr. Michael Hayden is a Killam Professor of Medical Genetics at the University of British Columbia and Canada Research Chair in Human Genetics and Molecular Medicine. He is also the Director of the Center for Molecular Medicine and Therapeutics (CMMT) in Vancouver, Canada; a genetic research center within UBC and located at the Child and Family Research Institute. Michael was the top graduate in medicine (1975) from the University of Cape Town, where he also received his PhD in Genetics (1979). He completed a post-doctoral fellowship and further training in Internal Medicine at Harvard Medical School. Michael is board-certified in both Internal Medicine and Clinical Genetics.
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Wednesday, 22 June 2011 19:54 |
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Shizuo Akira received his M.D. from Osaka University in 1977, and after three years' clinical training as physician, he entered the Graduate School of Medicine, Osaka University in 1980, and obtained his Ph.D. in 1984. He spent two years from 1985 to 1987 as a postdoctoral fellow at the Department of Microbiology and Immunology, University of California at Berkeley. He was a research associate from 1987 through 1995 at the Institute for Molecular and Cellular Biology, Osaka University in the laboratory of Dr. Tadamitsu Kishimoto, where he cloned two transcription factors, NF-IL6(C/EBPbeta) and STAT3.
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Wednesday, 01 June 2011 06:56 |
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The Wiley Prize in Biomedical Sciences is intended to recognize breakthrough research in pure or applied life science research that is distinguished by its excellence, originality and impact on our understanding of biological systems and processes. The award may recognize a specific contribution or series of contributions that demonstrate the nominee’s significant leadership in the development of research concepts or their clinical application. Particular emphasis will be placed on research that champions novel approaches and challenges accepted thinking in the biomedical sciences.
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Wednesday, 18 May 2011 08:11 |
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The Wiley Prize in Biomedical Sciences is intended to recognize breakthrough research in pure or applied life science research that is distinguished by its excellence, originality and impact on our understanding of biological systems and processes. The award may recognize a specific contribution or series of contributions that demonstrate the nominee’s significant leadership in the development of research concepts or their clinical application. Particular emphasis will be placed on research that champions novel approaches and challenges accepted thinking in the biomedical sciences.
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Wednesday, 12 October 2011 03:10 |
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Prof. Thomas Pollard pioneered the biochemical and biophysical analysis of the actin cytoskeleton, which is responsible for form and movement in all cells. His many contributions have defined the actin cytoskeleton field for nearly three decades, and include the basis for directional actin polymerization, the discovery of actin capping, severing and nucleation factors and the mechanisms of actin-based intracellular movement. The complex actin-based cytoskeletal network underlies cell shape and motility in virtually all biological contexts, including intracellular transport, polarized cell growth and division, tissue formation and developmental morphogenesis. In addition, actin dynamics is essential for virulence of a number of human bacterial pathogens.
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Thursday, 29 September 2011 02:27 |
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Dennis Slamon's work exemplifies translational research of the highest order. He has taken a basic research finding, HER2/neu oncogenes, and developed a better understanding of how this marker serves as a surrogate for prognosis, a therapeutic target, and a predictive test for therapeutic outcome. His work has saved the lives of thousands of women. Herceptin has provided a paradigm shift in the field of cancer therapy by showing that drugs can be developed against defects present in specific cancers.
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Thursday, 08 September 2011 02:53 |
Dr. Samuel Weiss is Professor and Alberta Heritage Foundation for Medical Research (AHFMR) Scientist in the Departments of Cell Biology & Anatomy and Pharmacology & Therapeutics at the University of Calgary Faculty of Medicine. He is the inaugural Director of the Hotchkiss Brain Institute, a partnership between the Faculty of Medicine and the Calgary Health Region, whose mission is to translate innovative research and education into advances in neurological and mental health care.
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Wednesday, 24 August 2011 22:13 |
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Richard Losick is the Maria Moors Cabot Professor of Biology, a Harvard College Professor, and a Howard Hughes Medical Institute Professor in the Faculty of Arts & Sciences at Harvard University. He received his A.B. in Chemistry at Princeton University and his Ph.D. in Biochemistry at the Massachusetts Institute of Technology. Upon completion of his graduate work, Professor Losick was named a Junior Fellow of the Harvard Society of Fellows when he began his studies on RNA polymerase and the regulation of gene transcription in bacteria. Professor Losick is a past Chairman of the Departments of Cellular and Developmental Biology and Molecular and Cellular Biology at Harvard University.
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Wednesday, 10 August 2011 23:34 |
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Dr. Semenza received undergraduate training (A.B.) in Biology at Harvard College; M.D. and Ph.D. degrees from the University of Pennsylvania; Pediatrics residency training at Duke University Medical Center; and postdoctoral training in Medical Genetics at The Johns Hopkins University School of Medicine, where he has spent his entire career. He is currently the C. Michael Armstrong Professor at Johns Hopkins with appointments in Pediatrics, Medicine, Oncology, Radiation Oncology, Biological Chemistry, and the McKusick-Nathans Institute of Genetic Medicine.
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Monday, 25 July 2011 23:17 |
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William G. Kaelin Jr. is a Professor in the Department of Medicine at the Dana-Farber Cancer Institute and at the Brigham and Women's Hospital, Harvard Medical School, where he currently serves as Associate Director, Basic Science, for the Dana-Farber/Harvard Cancer Center. He obtained his undergraduate and M.D. degrees from Duke University and completed his training in internal medicine at the Johns Hopkins Hospital, where he served as chief medical resident. He was a clinical fellow in medical oncology at the Dana-Farber Cancer Institute and later a postdoctoral fellow in the laboratory of David Livingston, during which time he was a McDonnell Scholar.
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Tuesday, 12 July 2011 18:46 |
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Robert E. Black, M.D., M.P.H. is the Edgar Berman Professor and Chair of the Department of International Health and Director of the Institute for International Programs of the Johns Hopkins Bloomberg School of Public Health in Baltimore, Maryland. Dr. Black is trained in medicine, infectious diseases and epidemiology. He has served as a medical epidemiologist at the Centers for Disease Control and worked at institutions in Bangladesh and Peru on research related to childhood infectious diseases and nutritional problems.
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Friday, 17 June 2011 19:39 |
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Adrian Bird holds the Buchanan Chair of Genetics at the University of Edinburgh and is Director of the Wellcome Trust Centre for Cell Biology. He graduated in Biochemistry from the University of Sussex UK and obtained his PhD at Edinburgh University. Following postdoctoral experience at the Universities of Yale and Zurich, he joined the Medical Research Council's Mammalian Genome Unit in Edinburgh.
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Wednesday, 25 May 2011 06:02 |
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The Wiley Prize in Biomedical Sciences is intended to recognize breakthrough research in pure or applied life science research that is distinguished by its excellence, originality and impact on our understanding of biological systems and processes. The award may recognize a specific contribution or series of contributions that demonstrate the nominee’s significant leadership in the development of research concepts or their clinical application. Particular emphasis will be placed on research that champions novel approaches and challenges accepted thinking in the biomedical sciences.
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Wednesday, 11 May 2011 06:22 |
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The Wiley Prize in Biomedical Sciences is intended to recognize breakthrough research in pure or applied life science research that is distinguished by its excellence, originality and impact on our understanding of biological systems and processes. The award may recognize a specific contribution or series of contributions that demonstrate the nominee’s significant leadership in the development of research concepts or their clinical application. Particular emphasis will be placed on research that champions novel approaches and challenges accepted thinking in the biomedical sciences.
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