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UPDATE 1-AstraZeneca places two new bets after R&D setbacks PDF Print E-mail
Thursday, 22 December 2011 07:39

* Pays $20 mln upfront for rights to Chi-Med cancer drug

* Signs option on new type of diabetes pill from Astellas

* Follows double dose of bad news on AZ pipeline on Tuesday

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Pfizer adds to fibrosis drug pipeline with Excaliard buyout PDF Print E-mail
Monday, 28 November 2011 02:12

Four years after opening shop with a $15.5 million Series A, Excaliard Pharmaceuticals is being snapped up by Pfizer ($PFE) after attracting the pharma giant's attention with a string of positive Phase II results for its lead anti-fibrotic antisense drug.

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Ablynx Signs Discovery Pact Worth $69 Million With Merck Serono PDF Print E-mail
Thursday, 10 November 2011 06:12

GHENT, BELGIUM--(Marketwire - November 09, 2011) - Ablynx [Euronext Brussels: ABLX] today announced that it has further expanded its relationship with Merck Serono, a division of Merck KGaA, Darmstadt, Germany, and entered into a third agreement to co-discover and co-develop Nanobodies(®) against two targets in osteoarthritis. The companies will exploit the unique Nanobody features and will develop multi-specific products, which have extended half-lives.

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Sanofi To Layoff Hundreds In Sales And R&D PDF Print E-mail
Thursday, 03 November 2011 07:17
http://en.sanofi.com/images/template/logo.jpgIn the aftermath of the Genzyme acquisition, Sanofi told employees this morning about plans to shift various R&D operations between New Jersey and Massachusetts, as well as scaling back the sales force, primarily in the cardiovascular and oncology groups. All told, hundreds of jobs will be eliminated, although a spokesman was unable to specify the actual number until more details are sorted out.
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Nephron Pharmaceuticals Plans $313 Million Expansion; Will Create 700+ New Jobs PDF Print E-mail
Sunday, 30 October 2011 22:53
ORLANDO, FL – October 28, 2011 – Nephron Pharmaceuticals Corporation today announced expansion plans that involve constructing new pharmaceutical operations in Lexington County, SC. The planned $313 million investment is expected to generate 707 new jobs. The new
pharmaceutical campus will be located a few miles outside of Columbia, SC along Interstates 26 and 77.
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Life Tech Inks CDx Deal with GlaxoSmithKline; Gets China OK for 3500 Dx Genetic Analyzers PDF Print E-mail
Wednesday, 26 October 2011 20:01
Life Technologies has forged a partnership with GlaxoSmithKline Biologicals to develop a companion diagnostic test for GSK's candidate cancer immunotherapy, and gained regulatory approval in China for its Applied Biosystems 3500 Dx/3500xL Dx Genetic Analyzer, it announced separately after the close of the market on Tuesday.
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Novartis to Cut 2,000 Swiss, U.S. Jobs, Add Positions in China PDF Print E-mail
Tuesday, 25 October 2011 06:56

Oct. 25 (Bloomberg) -- Novartis AG, Europe's second-biggest pharmaceutical company, plans to eliminate 2,000 jobs in Switzerland and the U.S. and add employees in China and India to offset the effect of drug-price reductions.

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Dynavax Technologies Corporation and GlaxoSmithKline Expand Their Worldwide Strategic Alliance to Up to $203 Million PDF Print E-mail
Sunday, 23 October 2011 00:55
RKELEY, CA, Oct 21, 2011 (MARKETWIRE via COMTEX) -- Dynavax Technologies Corporation announced today the expansion of its worldwide strategic alliance with GlaxoSmithKline (GSK) focused on toll-like receptor (TLR) inhibitors. The addition of a new target, TLR8, entitles Dynavax to receive a $3 million milestone payment from GSK. Subject to reaching sales and development milestones, Dynavax has the potential to receive approximately $200 million in milestone payments over the term of the alliance. Based on preclinical data, Dynavax and GSK will work to develop a TLR8 inhibitor for the treatment of multiple autoimmune and inflammatory diseases.
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Auris Medical AG Reporting Positive Results from Phase 2b Trial With AM-101 for the Treatment of Acute Inner Ear Tinnitus PDF Print E-mail
Thursday, 20 October 2011 00:42
Auris Medical announced today positive results from a phase IIb clinical trial with AM-101, its investigational drug for the intratympanic treatment of acute inner ear tinnitus. The study demonstrated that the treatment was very well tolerated and showed a statistically significant treatment effect. 
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KV Pharmaceutical Sues Former CEO $37 Million in Benefits PDF Print E-mail
Thursday, 20 October 2011 00:37

KV Pharmaceutical Co. has filed a lawsuit against its former board chairman and chief executive, Marc Hermelin, hoping to avoid paying him about $36.9 million in retirement benefits, plus legal expenses.

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UPDATE: Ocimum Biosolutions/Gene Logic Files for Chapter 11, Seeks Bidders PDF Print E-mail
Thursday, 15 December 2011 05:52

NEW YORK (GenomeWeb News) – Ocimum Biosolutions, doing business as Gene Logic, has filed for Chapter 11 bankruptcy protection, and is seeking a buyer for its assets.

The US subsidiary filed for Chapter 11 in mid-October, and according to Jeffrey Carbino, a lawyer representing Ocimum in its bankruptcy proceedings, an auction of substantially all of the assets of Ocimum/Gene Logic, is scheduled for Jan. 6, 2012, with a Jan. 4 deadline for submitted bids. On Jan. 10, a sale hearing is scheduled in US Bankruptcy Court for the District of Delaware.

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Geron Shuts Down Pioneering Stem-Cell Program PDF Print E-mail
Wednesday, 16 November 2011 01:55

http://www.geron.com/@ssets/images/header/headerlogo.pngA study of whether embryonic stem cells could cure spinal-cord injury suffered from high costs, dim prospects.

Biotechnology firm Geron said last night that it would discontinue its stem-cell research program and halt a pioneering clinical study in people with spinal-cord injury.

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Mylan Inc. to Buy Respiratory Products from Pfizer Inc. for $17.5 Million, Will Hire Former Pfizer Employees to Meet Needs of New Division PDF Print E-mail
Thursday, 10 November 2011 05:47
Mylan Inc. (Nasdaq: MYL) today announced that it has entered into an agreement with Pfizer for the exclusive worldwide rights to develop, manufacture and commercialize Pfizer's generic equivalent to GlaxoSmithKline's Advair® Diskus and Seretide® Diskus incorporating Pfizer's proprietary dry powder inhaler delivery platform. Advair® Diskus and Seretide® Diskus are inhaled fixed-dose combinations of Fluticasone Propionate and Salmeterol delivered via a dry powder inhaler and are used to treat asthma and COPD (chronic obstructive pulmonary disorder).
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GSK sets stage for big late-stage drug events, potential blockbusters PDF Print E-mail
Wednesday, 02 November 2011 06:49

GlaxoSmithKline ($GSK) has taken some bold steps to reconfigure its R&D operations, tackling some of the productivity issues that have plagued Big Pharma groups. Over the next year, the London-based drug giant has many big Phase III events in store that could make its pipeline the envy of the industry.

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Biogen Idec, Inc. (Massachusetts), Portola Pharmaceuticals, Inc. Strike $553 Million Deal for Oral Syk Inhibitor PDF Print E-mail
Friday, 28 October 2011 06:24
WESTON, Mass. & SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)-- Biogen Idec (NASDAQ:BIIB - News) and Portola Pharmaceuticals, Inc. today announced that they have entered into an exclusive, worldwide collaboration and license agreement under which both companies will develop and commercialize highly selective, novel oral Syk inhibitors for the treatment of various autoimmune and inflammatory diseases, including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE).
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Illumina to Cut 200 Jobs from Global Workforce PDF Print E-mail
Wednesday, 26 October 2011 19:34
Following yesterday's announcement that its third-quarter revenues fell 1 percent and that it would undertake a restructuring, Illumina filed a document with the US Securities and Exchange Commission disclosing that it will cut 200 jobs from its global workforce.
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Merck KGaA to Return Safinamide Rights to Newron Pharmaceuticals, Citing "Limited Market Potential" PDF Print E-mail
Monday, 24 October 2011 00:46

Newron Pharmaceuticals S.p.A. (“Newron”), a research and development company focused on novel CNS and pain therapies, announced today that Merck Serono, a division of Merck KGaA, Darmstadt Germany, is returning global rights to safinamide to Newron effective in 180 days. The decision by Merck Serono is due to strategic considerations and re-prioritization of its R&D pipeline, and is not based on any new efficacy or safety findings with safinamide.

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Allos Therapeutics, Inc., AMAG Pharmaceuticals, Inc. Merger Called Off PDF Print E-mail
Sunday, 23 October 2011 00:51
WESTMINSTER, Colo.--(BUSINESS WIRE)-- Allos Therapeutics, Inc. (Nasdaq:ALTH - News) announced today that the Agreement and Plan of Merger and Reorganization (“the Merger Agreement”) entered into by and among Allos, AMAG and Alamo Acquisition Sub, Inc. on July 19, 2011, as amended on August 8, 2011, has been terminated. The Merger Agreement was terminated following the October 21, 2011, special meeting of AMAG stockholders at which AMAG's stockholders voted against the issuance of shares of AMAG common stock to Allos’ stockholders in the proposed merger. Separately, a majority of Allos’ stockholders voted in favor of the adoption of the Merger Agreement at a special meeting of Allos stockholders also held on October 21, 2011.
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Lpath, Inc. Initiates Dosing of iSONEP in Second of Two Proof-of-Concept Trials PDF Print E-mail
Thursday, 20 October 2011 00:40
Lpath, Inc. (OTCBB: LPTN), the industry leader in lipidomics-based antibody therapeutics, has initiated dosing in its Nexus clinical trial, in which iSONEP™ is being investigated as a treatment for wet AMD (age-related macular degeneration).
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Takeda Pharmaceutical Co. Ltd. to Focus on Integration Versus Mergers for Near Future, Executive Says PDF Print E-mail
Wednesday, 19 October 2011 00:24

Takeda president Yasuchika Hasegawa said that following its acquisition of Nycomed, the drugmaker has no near-term plans for another large-scale merger and acquisition, The Wall Street Journal reported Friday. "We would like to focus on integration for the next year or two. We don't have the capacity for big acquisitions, but maybe small ones," he indicated.

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